Publications by authors named "Oluwatomi E Akingbade"
Accurate, reliable, and cost-effective immunosensors are clinically important for the early diagnosis and monitoring of progressive diseases, and multiplexed sensing is a promising strategy for the next generation of diagnostics. This strategy allows for the simultaneous detection and quantification of multiple biomarkers with significantly enhanced reproducibility and reliability, whilst requiring smaller sample volumes, fewer materials, and shorter average analysis time for individual biomarkers than individual tests. In this opinionated review, we compare different techniques for the development of multiplexed immunosensors.
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- GFAP is an important blood biomarker for neurological diseases, especially traumatic brain injury, but accurate detection in patient samples is currently lacking.
- A new graphene field-effect transistor (GFET) biosensing method has been developed to quickly and sensitively detect GFAP in patient plasma, achieving very low limits of detection.
- This GFET biosensor outperforms traditional methods like ELISA and other advanced technologies, offering faster results, cost-effectiveness, and ease of use, making it a promising option for point-of-care diagnostics.