Plasmodium yoelii as a model for malaria: insights into pathogenesis, drug resistance, and vaccine development.

Malaria continues to pose a serious global health threat, with rising drug resistance making treatment more difficult. Consequently, Plasmodium yoelii, a rodent malaria parasite, has become an invaluable model for studying the malaria parasite's complex biology, particularly host-parasite interactions and drug resistance mechanisms. Originating from African rodents, P.