Publications by authors named "Oluwaseye M Oladimeji"
Background: Recent evidence has linked changes in plasma lecithin-cholesterol acyltransferase (LCAT) and paraoxonase-1 (PON-1) levels with increased risk for development of premature atherosclerotic cardiovascular disease (ASCVD) in different populations. However, studies on this in Nigeria and sub-Saharan Africa are scarce.
Objective: This study assessed the association between reduced plasma LCAT and PON-1 levels and an increased risk of ASCVD, and their potential as biomarkers for ASCVD.
Article Synopsis
- Pregnancy leads to significant cardiovascular changes, particularly chronic volume overload, which can influence maternal health and is a major cause of non-obstetric maternal deaths worldwide.* -
- The study examines left and right ventricular and atrial size variations during pregnancy and postpartum in healthy women aged 18 to 40, utilizing clinical evaluations and echocardiography.* -
- Results indicate an increase in left ventricular wall thickness throughout pregnancy, with a notable decrease postpartum, while the left atrial size peaked in the third trimester.*
Background Heart failure contributes to the global burden of cardiovascular diseases, with hypertensive heart failure affecting individuals in their productive age group and leading to high economic losses and disability-adjusted life years. The left atrium, on the other hand, contributes significantly to left ventricular filling in heart failure patients, and the left atrial function index is an excellent tool for assessing left atrial function among heart failure patients. The study aimed to evaluate some parameters of systolic and diastolic function as correlates and potential predictors of the left atrial function index among hypertensive heart failure cohorts.
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