Hypoglycemia Prevention by Algorithm Design During Intravenous Insulin Infusion.

Purpose Of Review: This review examines algorithm design features that may reduce risk for hypoglycemia while preserving glycemic control during intravenous insulin infusion. We focus principally upon algorithms in which the assignment of the insulin infusion rate (IR) depends upon maintenance rate of insulin infusion (MR) or a multiplier.

Recent Findings: Design features that may mitigate risk for hypoglycemia include use of a mid-protocol bolus feature and establishment of a low BG threshold for temporary interruption of infusion.

Hypoglycemia Reduction Strategies in the ICU.

Purpose Of Review: We reviewed the strategies associated with hypoglycemia risk reduction among critically ill non-pregnant adult patients.

Recent Findings: Hypoglycemia in the ICU has been associated with increased mortality in a number of studies. Insulin dosing and glucose monitoring rules, response to impending hypoglycemia, use of computerization, and attention to modifiable factors extrinsic to insulin algorithms may affect the risk for hypoglycemia.