Publications by authors named "Oluwajoba Adegoke"
Objective: Flurbiprofen 8.75 mg lozenge and spray are used for symptomatic relief of sore throat, with a rapid onset of analgesia suggesting a localized mechanism of action. Building on previous studies, this investigation aimed to use microautoradiography to visualize the depth penetration of radiolabeled flurbiprofen into human pharynx tissue using an ex vivo model.
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- * Using a specialized lab model, researchers measured the flurbiprofen levels in different tissue layers over a 60-minute period and found both formulations were quickly detectable in the tissues.
- * Results indicated that flurbiprofen spray penetrated slightly differently than the lozenge, with a significant portion reaching deeper layers of the tissue, suggesting effective localized action for treating sore throats.
Objective: For the majority of people with acute sore throat, over-the-counter treatments represent the primary option for symptomatic relief. This study evaluated the in vitro bactericidal activity of lozenges containing the antiseptic hexylresorcinol against five bacteria associated with acute sore throat: Staphylococcus aureus, Streptococcus pyogenes, Moraxella catarrhalis, Haemophilus influenzae and Fusobacterium necrophorum.
Results: Hexylresorcinol 2.