Publications by authors named "Oluwadamilola Oni"
Article Synopsis
- Ecotin, initially found in E. coli, is a strong inhibitor of various serine proteases, including those involved in the immune response, like neutrophil elastase (NE).
- Researchers identified ecotin-like proteins in Campylobacter species linked to periodontal disease and studied their function by expressing them in E. coli and testing their inhibitory effects.
- It was discovered that C. rectus and C. showae ecotins can inhibit NE and support survival in an ecotin-deficient E. coli mutant, suggesting their potential role in protecting against proteases in the oral environment.
Cystic fibrosis (CF) airway disease is characterized by the long-term presence of neutrophil granulocytes. Formation of neutrophil extracellular traps (NETs) and/or autoantibodies directed against extracellular components of NETs are possible contributors to neutrophil-mediated lung damage in CF. The goal of this study was to measure their levels in CF adults compared to healthy controls and subjects with rheumatologic diseases known to develop NET-related autoantibodies and pathologies, rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
View Article and Find Full Text PDF