Publications by authors named "Oluseyi Kolawole"
Article Synopsis
- Overexpression of SNAI1, a key regulator of the epithelial-to-mesenchymal transition (EMT), is shown to play a significant role in the development of human acute myeloid leukemia (AML) by affecting cell differentiation and promoting the growth of immature myeloid cells.
- Research indicates that elevated SNAI1 levels can lead to increased self-renewal and proliferation of these cells, suggesting its importance in AML pathology.
- The study highlights a previously unknown interaction between SNAI1 and the histone demethylase KDM1A/LSD1, providing new insights into leukemia mechanisms and potential treatment strategies involving LSD1 inhibitors.
Lassa fever is a deadly viral haemorrhagic fever caused by Lassa Virus (LASV). Rodents, especially, , are the known reservoirs of LASV and humans are the defined hosts. Monkeys share many illnesses with humans and experimental LASV infections in monkeys are fatal but natural LASV infection of monkeys has not been reported.
View Article and Find Full Text PDF