Anti-inflammatory and analgesic effects of methanol extract of red cultivar bulbs in rats and mice.

Objectives: Several cultivars of L. have been studied for anti-inflammatory and analgesic activities but there is inadequate information on such biological activities of the concentrated extracts of the Nigerian grown red cultivar bulb.

Methods: The anti-inflammatory models used in this study were Carrageenan-induced paw oedema and formalin-induced paw lick in rats, while acetic acid-induced abdominal writhing, hot plate reaction, hot water tail flick tests in mice were the analgesic models.

Testicular and spermatotoxic potential of methanol extract of red cultivar Allium cepa in rats.

Background In both human and animals, especially in food and companion animal breeding farms, infertility is normally a challenge of great concern. Males have been found to be solely responsible for about 20-30% of infertility cases. Allium cepa (Onion), being one of the highly consumed spices worldwide, is usually overlooked as a possible reproductive toxicant.

Histomorphometry and Protein Expression From the Ovary and Uterine Horns of Wistar Strain Albino Rats Treated with Methanol Leave Extract of Parquetina Nigrescens.

Background: The effects of methanol extract of Parquetina nigrescens were studied on histomorphometry and protein expression (SDS-PAGE) from the ovaries and uteri of wistar rats.

Methods: 30 sexually matured rats were used for the study with 10 each in the control and treatment 100 mgkg and 400 mgkg groups. The extract was orally administered for 14 days.

Antihypertensive Effect of Polyphenol-Rich Fraction of Azadirachta indica on Nω-Nitro-L-Arginine Methyl Ester-Induced Hypertension and Cardiorenal Dysfunction.

(AI) is a medicinal plant with reported antioxidant and cardio-protective properties. The use of plant-based polyphenols has become greatly increased in the last one decade. The present study investigated the protective effect of the polyphenol-rich fraction (PRF) of the methanol-extract of against N-Nitro-L-Arginine Methyl Ester (L-NAME) induced hypertension and cardiorenal dysfunction in rats.

Effects of Trypanosoma brucei brucei infection and diminazene aceturate administration on the blood pressure, heart rate, and temperature of Wistar albino rats.

Background: This study was carried out to determine the blood pressure changes in experimentally Trypanosoma brucei brucei-infected Wistar albino rats and diminazene aceturate-treated rats.

Methods: Twenty-four rats were purchased and divided into four groups consisting of six rats each. Control group (CON) received 0.

Toxicological evaluation of the aqueous extract of Acalypha wilkesiana in Wistar albino rats.

Background: Acalypha wilkesiana (Euphorbiaceae) is highly accepted for traditional treatment of human plasmodiasis in Africa.

Methods: The toxicological effects of the aqueous leaf extract of A. wilkesiana were studied in 45 male and female Wistar albino rats.