Publications by authors named "Olukayode O Akpaja"

Article Synopsis
  • The aqueous extract of Pleurotus tuberregium (PT) was found to lower intraocular pressure (IOP), but its exact mechanism was previously unknown.
  • Research investigated PT's effects on bovine iris compared to acetylcholine (ACh) by examining their responses in organ baths.
  • Results indicated that both PT and ACh caused contractions in the iris, but higher concentrations diminished their effects, and atropine completely blocked these contractions, suggesting PT may work on muscarinic receptors to reduce IOP.
View Article and Find Full Text PDF