Innovative PEEK in Dentistry of Enhanced Adhesion and Sustainability through AI-Driven Surface Treatments.

This research investigates using Polyether ether ketone (PEEK) in dental prosthetics, focusing on enhancing the mechanical properties, adhesion capabilities, and environmental sustainability through AI-driven data analysis and advanced surface treatments. The objectives include improving PEEK's adhesion to dental types of cement, assessing its biocompatibility, and evaluating its environmental impact compared to traditional materials. The methodologies employed involve surface treatments such as plasma treatment and chemical etching, mechanical testing under ASTM standards, biocompatibility assessments, and lifecycle analysis.

AI-Driven Data Analysis of Quantifying Environmental Impact and Efficiency of Shape Memory Polymers.

This research investigates the environmental sustainability and biomedical applications of shape memory polymers (SMPs), focusing on their integration into 4D printing technologies. The objectives include comparing the carbon footprint, embodied energy, and water consumption of SMPs with traditional materials such as metals and conventional polymers and evaluating their potential in medical implants, drug delivery systems, and tissue engineering. The methodology involves a comprehensive literature review and AI-driven data analysis to provide robust, scalable insights into the environmental and functional performance of SMPs.

Advancing sustainable materials in a circular economy for decarbonisation.

This research paper delves into the intricate interplay between decarbonisation and sustainability, focusing on adopting chemical looping technologies. Deep decarbonisation scenarios necessitate a profound transformation in various sectors to mitigate climate change, and oil refineries, as pivotal players, must adapt to these changes. Employing the BLUES integrated assessment model, we evaluate the evolution of the refining sector in decarbonisation pathways, emphasising its potential for sustainability through repurposing and emissions mitigation.

Corrosion Performance of Wire Arc Additive Manufacturing of Stainless Steel: A Brief Critical Assessment.

To enhance the products fabricated from wire arc additive manufacturing (WAAM) processes, it is very important to implement a critical assessment of the corrosion performance of additively manufactured stainless steel (SS) for the application of additive manufacturing parts widely used in industries. The common defects in metal additive manufacturing, which include porosity, poor surface finish, oxidation, environmental factor, residual stress, and microstructural defects, are known to significantly influence the corrosion behavior of WAAM-processed SS components prepared to be used under different corrosive and marine environments. This article reviews the recently published works on WAAM-processed SS and provides a critical overview method to improve the corrosion performance of SS components built with the WAAM processes.

Sensing behavior change in chronic pain: a scoping review of sensor technology for use in daily life.

Technology offers possibilities for quantification of behaviors and physiological changes of relevance to chronic pain, using wearable sensors and devices suitable for data collection in daily life contexts. We conducted a scoping review of wearable and passive sensor technologies that sample data of psychological interest in chronic pain, including in social situations. Sixty articles met our criteria from the 2783 citations retrieved from searching.

Guarding and flow in the movements of people with chronic pain: A qualitative study of physiotherapists' observations.

Background: Among the adaptations of movement consistently associated with disability in chronic pain, guarding is common. Based on previous work, we sought to understand better the constituents of guarding; we also used the concept of flow to explore the description of un/naturalness that emerged from physiotherapists' descriptions of movement in chronic pain. The aim was to inform the design of technical systems to support people with chronic pain in everyday activities.

Neuroprotective flavonoids of the leaf of Antiaris africana Englea against cyanide toxicity.

Ethnopharmacological Relevance: Different parts of Antiaris africana Englea (Moraceae) are used traditionally for the treatment of various diseases, including epilepsy and other nervous system disorders.

Aims Of This Study: The current study was designed to evaluate the neuroprotective activity of flavonoids isolated from A. africana against potassium cyanide (KCN)-induced oxidative damage in brain homogenate.

Bridging the gap between emotion and joint action.

Our daily human life is filled with a myriad of joint action moments, be it children playing, adults working together (i.e., team sports), or strangers navigating through a crowd.

The relationship between guarding, pain, and emotion.

Introduction: Pain-related behavior in people with chronic pain is often overlooked in a focus on increasing the amount of activity, yet it may limit activity and maintain pain and disability. Targeting it in treatment requires better understanding of the role of beliefs, emotion, and pain in pain behavior.

Objectives: This study aimed to clarify the interrelationships between guarding, pain, anxiety, and confidence in movement in people with chronic pain in everyday movements.

Datasets on the corrosion behaviour of nanostructured AISI 316 stainless steel treated by SMAT.

The present paper contains the experimental datasets on the corrosion behaviour of nanostructured AISI 316 stainless steel (SS) through polarization tests in 0.6 M NaCl aqueous solution at room temperature. The nanostructured layers were first obtained through surface mechanical attrition treatment (SMAT) method and the data information on the corrosion behaviour of the nanostructured layer was thereafter collected.

Memory enhancing, anticholinesterase and antimicrobial activities of β-phenylnitroethane and essential oil of Dennettia tripetala Baker f.

Ethnopharmacological Relevance: Dennettia tripetala Baker f. belonging to the family Annonaceae is an important food and medicinal plant used in some local communities in Southwest Nigeria.

Aims Of The Study: The study aims at determining the chemical composition of the essential oil of different morphological parts of D.

Inter-individual variation in imatinib disposition: any role for prevalent variants of CYP1A2, CYP2C8, CYP2C9, and CYP3A5 in Nigerian CML patients?

Imatinib has been successful in the management of chronic myeloid leukemia (CML) but some patients experience adverse reactions or develop resistance to its use. The roles of some polymorphisms in genes encoding enzymes critical for the biotransformation of imatinib have been previously examined. This study, hence, evaluated some other unstudied functionally significant polymorphisms in CYP1A2, CYP2C8, CYP2C9, and CYP3A5.

Bidirectional Pharmacokinetic Interaction Between Amodiaquine and Pioglitazone in Healthy Subjects.

Amodiaquine (AQ) and pioglitazone (PGZ) are both metabolized by CYP2C8, an enzyme also inhibited by PGZ. These drugs are likely to be administered in instances of comorbidity of malaria with type 2 diabetes. This study, hence, evaluated the possibility of a drug interaction resulting from the concurrent use of both drugs.

Population Pharmacokinetics of Imatinib in Nigerians With Chronic Myeloid Leukemia: Clinical Implications for Dosing and Resistance.

Imatinib, a tyrosine kinase inhibitor, is the drug of choice for the treatment of chronic myeloid leukemia in Nigeria. Several studies have established interindividual and interpopulation variations in imatinib disposition although no pharmacokinetic study have been conducted in an African population since the introduction of the drug. This study explored a population pharmacokinetic approach to investigate the disposition of imatinib in Nigerians and examined the involvement of some covariates including genetic factors in the variability of the drug disposition with a view to optimize the use of the drug in this population.

Influence of CYP3A5*3 and ABCB1 C3435T on clinical outcomes and trough plasma concentrations of imatinib in Nigerians with chronic myeloid leukaemia.

What Is Known And Objective: Imatinib mesylate is the first-line drug for the treatment of Philadelphia/bcr-abl positive chronic myeloid leukaemia (CML). It is known to be metabolized mostly by CYP3A4 and CYP3A5 isoforms while its efflux is mediated by the transporters ABCB1 and ABCG2. Genetic polymorphism of some of these enzymes and transporters have been linked with inter-individual variations in the pharmacokinetics of the drug.

Hypnotic, anticonvulsant and anxiolytic effects of 1-nitro-2-phenylethane isolated from the essential oil of Dennettia tripetala in mice.

This study investigated the hypnotic, anti-convulsant and anxiolytic effects of 1-nitro-2-phenylethane (BPNE) obtained from the oil of Dennettia tripetala G. Baker (Annonaceae) and established its mechanism of action. The essential oil (EO) from the leaf, fruit and seed was obtained by hydrodistillation, followed by isolation of BPNE purified to 99.

New glucose esters from the fresh leaves of Jacaranda mimosaefolia.

From the fresh leaves of Jacaranda mimosaefolia were isolated Phytoquinoids 1-4 established as beta-D-glucopyranose 2-benzeneacetatel,6-bis(1-hydroxy-4-oxo-2,5-cyclohexadiene-1-acetate), for which the name Jacaranoside is proposed; beta-D-glucopyranose 2-(4-hydroxybenzeneacetate) 1,6-bis(1-hydroxy-4-oxo-2,5-cyclohexadiene-1-acetate), for which the name Jacarandol is proposed; beta-D-glucopyranose 2-benzeneacetate 1-(1-hydroxy-4-oxo-2,5-cyclohexadiene-1-acetate) and beta-D-glucopyranose 1,6-bis (1-hydroxy-4-oxo-2,5-cyclohexadiene-1-acetate) respectively.

Distribution of iridiod glucosides and anti-oxidant compounds in Spathodea campanulata parts.

The antioxidant principles isolated from the various parts of the plant are verminoside (leaf, stem bark and flowers; EC(50) = 2.04 µg/ml), Specioside (flowers; EC(50) = 17.44 µg/ml), Kampeferol diglucoside (leaf; EC(50) = 8.

Antinociceptive and antiinflammatory effects of essential oil of Dennettia tripetala G.Baker (Annonaceae) in rodents.

In this study we evaluated the analgesic and anti-inflammatory activities of the essential oil (EO) of the fruits of Dennettia tripetala in rodents. The plant is a tropical African plant and the fruits are commonly eaten as spices and consumed as a stimulant, and its various parts are used in the treatment of fever, cough and as anti-emetics.The analgesic effects of the oil was assessed in mice using the hot plate, acetic acid-induced writhings and formalin test, while carrageenan-induced paw oedema was used to study the antiinflammatory effects in rats.

Clinical evaluation of Acalypha ointment in the treatment of superficial fungal skin diseases.

In an open non-comparative study to evaluate the efficacy and safety of Acalypha wilkesiana ointment in superficial fungal skin diseases, 32 Nigerian patients with clinical and mycological evidence of superficial mycoses were recruited. Twelve patients defaulted and were lost to follow up, while one patient withdrew because of intolerable excoriation at the site of the lesion. Of the 19 patients that completed the trial, clinical cure was achieved in 73.

S. K. Adesina, O. Idowu, A. O. Ogundaini, H. Oladimeji, T. A. Olugbade, G. O. Onawunmi and M. Pais, 'Antimicrobial constituents of the leaves of EAcalypha wilkesiana and acalypha hispida'. Phytotherapy research14(5) 2000, 371-374.

The original article to which this Erratum refers was published in Phytotherapy Research 14(5) 2000, 371-374. Following publication of this paper in the August 2000 issue of Phytotherapy Research (14(5):371-374), it has come to our attention that the dates of receipt and acceptance were printed incorrectly. The corrected dates appear below.

Prieurianoside, a protolimonoid glucoside from the leaves of Trichilia prieuriana.

The ubiquitous glycolipid 1,2-dilinolenoyl-3-galactopyranosylglycerol and a new protolimonoid glucoside, named prieurianoside, were isolated from the leaves of Trichilia prieuriana. The structure of the latter was established, by spectroscopic techniques, as 12beta,21-diacetoxy-29-beta-D-glucopyranosyloxy-23zeta -hydroxytirucalla-7,24-dien-3-one.

Antimicrobial constituents of the leaves of Acalypha wilkesiana and Aacalypha hispida.

An activity directed fractionation of a 50% aqueous ethanol extract of A. wilkesiana and A. hispida leaves resulted in the isolation of gallic acid, corilagin and geraniin as the compounds responsible for the observed antimicrobial activity.

Petersaponins III and IV, triterpenoid saponins from Petersianthus macrocarpus.

Two new triterpenoid saponins, petersaponins III and IV (1 and 2), were isolated from an n-butanol extract of the bark of Petersianthus macrocarpus. They possess 21-O-benzoyl-22-O-acetylbarringtogenol C and 21-O-2-furoxyl-22-O-tigloylbarringtogenol C as the aglycon, respectively. For both 1 and 2, the trisaccharide moiety linked to C-3 of the aglycon consists of D-glucuronic acid, D-xylose, and D-galactose, while a L-rhamnose unit is linked to C-28.

New amides from Zanthoxylum lemairie pericarps.

Two new aromatic amides were isolated from the pericarps of Zanthoxylum lemairie. The structures were elucidated by spectroscopic methods and confirmed by synthesis. A known aromatic amide, zanthosinamide, and four dibenzylbutyrol-actone lignans were isolated.