Publications by authors named "Olufemiwa N Makinde"

Article Synopsis
  • - Hypertensive disorder of pregnancy (HDP) affects 10% of pregnancies globally and includes conditions like chronic hypertension and preeclampsia, leading to serious health risks for both mothers and infants.
  • - A study examining brachial artery flow-mediated dilation (BAFMD) showed that women with HDP had significantly lower BAFMD compared to normotensive pregnant and nonpregnant women, though no major differences were found between HDP subgroups.
  • - While BAFMD decreased with gestational age, it proved to be a poor indicator for HDP, with body mass index (BMI) identified as a better predictor for the condition.
View Article and Find Full Text PDF

Background: There is no consensus on the preferred time to remove urethral catheter post caesarean section.

Aim: To compare rate of significant bacteriuria and urinary retention following 8-h (study) and 24-h urethral catheter removal (control) post elective caesarean section.

Methods: A randomized controlled trial of eligible participants that underwent elective caesarean section under spinal anaesthesia between March 2019 and November 2019 was conducted.

View Article and Find Full Text PDF

Background: The purposes of this study are to sonographically measure the placental thickness (PT) in normal fetuses; to correlate it with gestational age (GA), fetal growth parameters, and estimated fetal weight (EFW); and to design a nomogram for the derived PT measurements.

Methods: This was a hospital-based cross-sectional study on 400 women with apparently normal pregnancy within the age range of 18-45 years recruited from the Antenatal Clinic of our hospital. The fetal GA was estimated by the last menstrual period (LMP).

View Article and Find Full Text PDF

Objective: To compare the expression of estrogen receptor α (ERα) and progesterone receptor (PR) in myometrium and leiomyomata tissue, and to correlate their expression with symptoms of uterine leiomyomata.

Methods: In a cross-sectional study, intraoperative biopsy samples of leiomyomata and adjacent myometrial specimens were obtained from premenopausal women with uterine leiomyomata treated at a center in Nigeria between September 2013 and August 2014. Immunohistochemistry for ERα and PR expression was performed on the samples.

View Article and Find Full Text PDF

Background: To evaluate the renal arterial hemodynamic changes caused by pregnancy-induced hypertension using Doppler ultrasonography.

Materials And Methods: Eighty (80) subjects with pregnancy-induced hypertension (PIH) and 160 controls (80 pregnant normotensive women and 80 healthy, non-pregnant women) underwent triplex renal sonography prospectively to determine their renal volumes and right renal artery Doppler indices.

Results: The peak systolic velocity, end diastolic velocity, pulsatility index, systolic/diastolic ratio and acceleration time were respectively significantly higher in the PIH group (68.

View Article and Find Full Text PDF

Objective: To determine the prevalence of gallstone disease and its complications among pregnant women in a semi-urban Nigerian setting.

Methods: Consecutive consenting pregnant women presenting at the prenatal clinic of a Nigerian tertiary hospital were recruited over an 18-month period. During routine obstetric ultrasound, the presence of gallstones and/or associated sequelae was investigated.

View Article and Find Full Text PDF