Predicted Reference Equations for Spirometry Indices as a Proxy from Anthropometry Measurements of Nigerian Children with Sickle Cell Anaemia Aged 5-12 Years.

Background: Significant morbidity and mortality in patients with sickle cell disease are accounted for by lung complications. To facilitate good respiratory care for children with sickle cell anaemia the generation of local predicted values is highly important.

Objective: To determine the reference equations for spirometry indices estimation in children with sickle cell anaemia, which can be readily used as proxy when there is no easy accessibility to spirometer.