Publications by authors named "Olubunmi Ayelagbe"

Article Synopsis
  • * Significant reductions in various blood components were found in HIV-positive individuals, while their APAF-1 levels were elevated, especially in those with the lowest CD4+ counts.
  • * The findings suggest that APAF-1 may play a role in CD4+ cell depletion and could be used as a diagnostic biomarker to monitor HIV/AIDS progression.
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Background And Aims: With the global rise in type 2 diabetes, predictive modeling has become crucial for early detection, particularly in populations with low routine medical checkup profiles. This study aimed to develop a predictive model for type 2 diabetes using health check-up data focusing on clinical details, demographic features, biochemical markers, and diabetes knowledge.

Methods: Data from 444 Nigerian patients were collected and analysed.

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Hemoglobin (Hb) and iron are prooxidants in nature and sources of free radicals in the biological system of all Hb phenotypes. Recent evidence linked abnormal hemoglobin S and C (HbSC) in sickle cell disease (SCD) to various complications in multiple oxidative processes. However, similar studies in relation to abnormal Hb traits are sparse.

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Consumption of soy products is speculated to reduce the risk and progression of some disease conditions. The underlying mechanisms mediating this effect are uncertain, but the lowering of oxidative stress has been suggested. This study was aimed at investigating the effect of soymilk on antioxidant status and lipid peroxidation in apparently healthy individuals.

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