- Monkeypox virus (MPXV) can spread through direct contact with lesions, respiratory secretions, fomites, and even from the mother to fetus during pregnancy, leading to painful skin lesions in infected individuals.
- In 2021-2022, the CDC began investigating aircraft after reports of travelers with mpox, collecting data from a total of 113 infected individuals who traveled on 221 flights during their infectious period.
- Despite these investigations, no cases of mpox transmission were reported from flight exposures, suggesting air travel with an infected person poses minimal risk; however, the CDC still advises isolation for those infected and postponing travel until they are no longer contagious.