Publications by authors named "Olubukola T Adenubi"

Article Synopsis
  • Pesticide exposure, specifically from Chlorpyriphos, causes significant reproductive issues in male rats by damaging their sex organs and reducing hormone levels, sperm quality, and testicular glycogen.
  • The study examined the effect of flavonoids (diosmin and hesperidin) on recovering reproductive functions in male Wistar rats after they were exposed to Chlorpyriphos for 60 days.
  • Results showed that the rats treated with flavonoids had notably better levels of reproductive hormones, improved sperm parameters, and higher testicular glycogen compared to those treated only with Chlorpyriphos, indicating the potential protective effects of these antioxidant compounds against pesticide toxicity.
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Ethnopharmacological Relevance: Lichens, a unique symbiotic association between an alga/cyanobacterium and a fungus, produce secondary metabolites that are a promising source of novel drug leads. The beauty and importance of lichens have not been adequately explored despite their manifold biological activities such as anticancer, antimicrobial, antioxidant, anti-inflammatory, analgesic, antipyretic and antiparasitic.

Aim Of The Study: The present review collates and discusses the available knowledge on secondary metabolites and biological activities of lichens (in vitro and in vivo).

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Introduction: Coronavirus disease (COVID-19) is impacting social, economic and political patterns globally. To contain its spread, Nigeria like many other countries, imposed drastic measures such as lockdown/curfew.

Objectives: This study assessed the knowledge, attitude and perception (KAP) about COVID-19 pandemic among members of staff of a university community in Nigeria.

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Article Synopsis
  • The study focused on knowledge and practices regarding COVID-19 among undergraduate veterinary students in Nigeria.
  • A web survey of 437 students revealed that while many had good overall knowledge (63.4%) and satisfactory practices (88.8%), adherence to key preventive measures was notably low.
  • Factors such as being in the 6th year of study and being female positively influenced knowledge and practices, indicating the need for improved awareness campaigns about COVID-19.
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Ticks are of great economic importance to humans and animals due to their role in disease transmission. The application of synthetic, chemical acaricides on the animal and/or the environment (the most used tick control method globally) has led to the selection of tick populations that are resistant. Their adverse effects on ecology and human and animal health cannot be overemphasised.

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Hot water and hydroethanolic (70:30) extracts were prepared from 15 plant species, which were investigated to discover eco-friendly and less expensive tick control methods as an alternative to synthetic acaricides. A contact bioassay was used to determine the acaricidal activity of these extracts against the cattle tick, Rhipicephalus turanicus (Acari: Ixodidae) at a concentration of 20% (200 mg/mL). The hydroethanolic extracts had better activity than the hot water extracts against R.

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The menace caused by ticks and tick-borne diseases is a major limitation to the livestock industry in Africa. The high costs and non-availability of synthetic, chemical acaricides to resource-limited farmers, resistance of ticks to available acaricides and residue problems in meat and milk consumed by humans further complicate matters. The use of plant extracts as a possible source of new acaricides has received much interest in the last decade.

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Ticks are haematophagous arthropods which rank closely with mosquitoes in their capacity to transmit disease pathogens of importance to animals and humans. Current control of ticks is based on the routine use of synthetic chemicals administered to animals or their environment. However, years of use and overuse of these chemicals have resulted in the development of resistance in these parasites and negative environmental impacts, hence the need for cheaper, safer and more environmentally friendly alternatives with alternate modes of action.

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The acaricidal activity of acetone and ethanol extracts of 12 plant species was evaluated using the contact method on Rhipicephalus turanicus (Acari: Ixodidae) ticks at an initial concentration of 20% (200 mg/mL). Eight of the 12 plants had mortality greater than 50% and the acetone extracts had better acaricidal activity than the ethanol extracts. The acetone extract of Calpurnia aurea (leaves and flowers) had the highest corrected mortality (CM) of 92.

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The goal of our research is to develop a lower cost eco-friendly tick control method because acaricides that are commonly used to control ticks are often toxic, harmful to the environment or too expensive for resource-limited farmers. Acetone and ethanol extracts were prepared and their acaricidal activities determined against the southern cattle tick, Rhipicephalus (Boophilus) microplus. A 1% solution of each of the plant extracts was prepared for efficacy testing using the adapted Shaw Larval Immersion Test (SLIT).

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The nematode, Haemonchus contortus, is responsible for major economic losses in the livestock industry. The management of parasites such as H. contortus has been through the use of synthetic parasiticides.

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The African blue tick, Rhipicephalus (Boophilus) decoloratus, is a common tick species found in South Africa and affects cattle production as well as vectoring pathogens in regions of Africa and Asia. In an attempt to develop a non-toxic, lower cost and environmentally friendly tick control method, twenty-six plant extracts were prepared from thirteen plant species using 99.5% acetone and 99% ethanol.

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Introduction: Since the first case of Ebola virus disease (EVD) in Guinea in 2013, major outbreaks have been reported in West Africa.

Methodology: Cases and fatalities of EVD caused by Zaire Ebola virus (ZEBOV) were evaluated, and the risks of dying in the general population and in healthcare workers were assessed.

Results: The case fatality rate estimated for EVD was 76.

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Background: This study was carried out to evaluate the anti-inflammatory and the analgesic potentials of Acalypha wilkesiana leaf extract in experimental animals.

Methods: The anti-inflammatory potential was investigated using an acute rat model. Aspirin at 150 mg/kg, indomethacin at 10 mg/kg as positive control, and methanolic extracts and solvent fractions of A.

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Objective: To evaluate the influence of premedication with tramadol on xylazine-ketamine anaesthesia in young pigs.

Study Design: Prospective, randomized, blinded cross-over study.

Animals: Ten young Niger hybrid pigs: mean weight 6.

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