Publications by authors named "Oltjon Taku"
J Am Soc Nephrol
October 2015
Article Synopsis
- Nephrin is essential for kidney development, specifically for the maturation of podocytes and the formation of the slit diaphragm junction, and its deficiency is linked to glomerular injury in diseases.
- Short-term reduction of nephrin did not impact kidney structure or function, while long-term knockdown led to significant kidney issues, including proteinuria and structural changes.
- Mice with reduced nephrin showed worsened kidney damage in response to additional injury factors, highlighting nephrin's role in maintaining kidney function and podocyte health.
