Silver nanoparticle (AgNP) assemblies combined with electrode surfaces have a myriad of applications in electrochemical energy storage and conversion devices, (bio)sensor development, and electrocatalysis. Among various nanoparticle synthesis methods, electrochemical deposition is advantageous due to its ability to control experimental parameters, enabling the formation of low-nanoscale (<50 nm) particles with narrow size distributions. Herein, we report the electrodeposition of AgNPs on a unique electrode platform based on carbon ultramicroelectrode arrays (CUAs), exploring several experimental variables including potential, time, and silver ion concentration.
View Article and Find Full Text PDFElectrode surfaces functionalized with gold nanoparticles (AuNP) are widely used in electroanalysis, electrocatalysis, and electrochemical biosensing due to their increased surface area and conductivity. Electrochemical deposition of AuNPs offers advantages over chemical synthesis, including better control over AuNP size, dispersion, and morphology. This study examines the electrodeposition of AuNPs on carbon ultramicroelectrode arrays (CUAs) focusing on electrodeposition parameters, such as deposition potential, deposition time, and gold ion concentration.
View Article and Find Full Text PDFThe monitoring of stress levels in humans has become increasingly relevant, given the recent incline of stress-related mental health disorders, lifestyle impacts, and chronic physiological diseases. Long-term exposure to stress can induce anxiety and depression, heart disease, and risky behaviors, such as drug and alcohol abuse. Biomarker molecules can be quantified in biological fluids to study human stress.
View Article and Find Full Text PDFBioelectrocatalytic synthesis is the conversion of electrical energy into value-added products using biocatalysts. These methods merge the specificity and selectivity of biocatalysis and energy-related electrocatalysis to address challenges in the sustainable synthesis of pharmaceuticals, commodity chemicals, fuels, feedstocks and fertilizers. However, the specialized experimental setups and domain knowledge for bioelectrocatalysis pose a significant barrier to adoption.
View Article and Find Full Text PDFRedox flow battery (RFB) electrolyte degradation is a common failure mechanism in RFBs. We report an RFB using genetically engineered, phenazine-producing to serve as an anolyte regeneration system capable of repairing the degraded/decomposed redox-active phenazines. This work represents a new strategy for improving the stability of RFB systems because, under the influence of genetically engineered microbes, the anolyte species does not display degradation after battery cycling.
View Article and Find Full Text PDFPhenazines are redox-active nitrogen-containing heterocyclic compounds that can be produced by either bacteria or synthetic approaches. As an electron shuttles (mediators), phenazines are involved in several biological processes facilitating extracellular electron transfer (EET). Therefore, it is of great importance to understand the structural and electronic properties of phenazines that promote EET in microbial electrochemical systems.
View Article and Find Full Text PDFPhotobioelectrocatalysis (PBEC) adopts the sophistication and sustainability of photosynthetic units to convert solar energy into electrical energy. However, the electrically insulating outer membranes of photosynthetic units hinder efficient extracellular electron transfer from photosynthetic redox centers to an electrode in photobioelectrocatalytic systems. Among the artificial redox-mediating approaches used to enhance electrochemical communication at this biohybrid interface, conducting redox polymers (CRPs) are characterized by high intrinsic electric conductivities for efficient charge transfer.
View Article and Find Full Text PDFHalophilic bacteria are remarkable organisms that have evolved strategies to survive in high saline concentrations. These bacteria offer many advances for microbial-based biotechnologies and are commonly used for industrial processes such as compatible solute synthesis, biofuel production, and other microbial processes that occur in high saline environments. Using halophilic bacteria in electrochemical systems offers enhanced stability and applications in extreme environments where common electroactive microorganisms would not survive.
View Article and Find Full Text PDFOver the past two decades, the designs of redox polymers have become critical to the field of mediated bioelectrocatalysis and are used in commercial glucose biosensors, as well as other bioelectrochemical applications (e.g., energy harvesting).
View Article and Find Full Text PDFThe development of electrochemical catalytic conversion of 5-hydroxymethylfurfural (HMF) has recently gained attention as a potentially scalable approach for both oxidation and reduction processes yielding value-added products. While the possibility of electrocatalytic HMF transformations has been demonstrated, this growing research area is in its initial stages. Additionally, its practical applications remain limited due to low catalytic activity and product selectivity.
View Article and Find Full Text PDFThe targeted diagnosis and effective treatments of chronic skin wounds remain a healthcare burden, requiring the development of sensors for real-time monitoring of wound healing activity. Herein, we describe an adaptable method for the fabrication of carbon ultramicroelectrode arrays (CUAs) on flexible substrates with the goal to utilize this sensor as a wearable device to monitor chronic wounds. As a proof-of-concept study, we demonstrate the electrochemical detection of three electroactive analytes as biomarkers for wound healing state in simulated wound media on flexible CUAs.
View Article and Find Full Text PDFBioelectrocatalysis is an interdisciplinary research field combining biocatalysis and electrocatalysis via the utilization of materials derived from biological systems as catalysts to catalyze the redox reactions occurring at an electrode. Bioelectrocatalysis synergistically couples the merits of both biocatalysis and electrocatalysis. The advantages of biocatalysis include high activity, high selectivity, wide substrate scope, and mild reaction conditions.
View Article and Find Full Text PDFMicrobial infections remain the principal cause for high morbidity and mortality rates. While approximately 1400 human pathogens have been recognized, the majority of healthcare-associated infectious diseases are caused by only a few opportunistic pathogens (e.g.
View Article and Find Full Text PDFThe opportunistic human pathogen Pseudomonas aeruginosa (Pa) causes several infections acquired in a healthcare setting. During initial stages of infection, Pa produces redox-active phenazine metabolites, including pyocyanin (PYO), 5-methylphenazine-1-carboxylic acid (5-MCA), and 1-hydroxyphenazine (OHPHZ), which have toxic effects on surrounding host cells and/or other microbes. Rapid and sensitive detection of these metabolites provides important evidence about the onset of Pa infections.
View Article and Find Full Text PDFHere, we use a recently developed electrochemical sensing platform of transparent carbon ultramicroelectrode arrays (T-CUAs) for the in vitro detection of phenazine metabolites from the opportunistic human pathogen Pseudomonas aeruginosa. Specifically, redox-active metabolites pyocyanin (PYO), 5-methylphenazine-1-carboxylic acid (5-MCA), and 1-hydroxyphenazine (OHPHZ) are produced by P. aeruginosa, which is commonly found in chronic wound infections and in the lungs of cystic fibrosis patients.
View Article and Find Full Text PDFPyocyanin is a virulence factor produced as a secondary metabolite by the opportunistic human pathogen, Pseudomonas aeruginosa. Fast and direct detection of pyocyanin is of importance as it could provide important insights regarding P. aeruginosa's virulence mechanisms.
View Article and Find Full Text PDFTransparent carbon ultramicroelectrode arrays (T-CUAs) were made using a previously reported facile fabrication method (Duay et al. Anal. Chem.
View Article and Find Full Text PDF© LitMetric 2025. All rights reserved.