Publications by authors named "Olivija Dobiliene"
Article Synopsis
- * In a study with 92 patients experiencing acute coronary syndromes, about 29% were identified as poor metabolizers of the CYP2C19 gene, which resulted in a significantly lower response to atorvastatin treatment compared to normal metabolizers.
- * The findings suggest that factors like the CYP2C19 metabolizing phenotype, patient age, and smoking status can increase the risk of inadequate treatment outcomes, highlighting the importance of tailoring atorvastatin therapy based on genetic profiles.
Background/objectives: To investigate the associations between ophthalmic parameters, CYP4F2 (rs2108622) and ABCA1 (rs1883025) polymorphisms and coronary artery disease, considering the accessibility, non-invasive origin of retinal examination and its possible resemblance to coronary arteries.
Subjects/methods: Overall 165 participants divided into groups based on the coronary angiography results and clinical status: control group (N = 73), MI group (N = 63), 3VD (three vessel disease) (N = 24). All the participants underwent total ophthalmic examination - optical coherence tomography (OCT) and OCT angiography of the macula region were performed and evaluated.
Background: Left ventricular global longitudinal strain (LV GLS) is a superior predictor of adverse cardiac events in patients with myocardial infarction and heart failure. We investigated the ability of morphological features of infarcted myocardium to detect acute left ventricular (LV) dysfunction and predict LV functional recovery after three months in patients with acute ST-segment elevation myocardial infarction (STEMI).
Methods: Sixty-six STEMI patients were included in the C-reactive protein (CRP) apheresis in Acute Myocardial Infarction Study (CAMI-1).
Article Synopsis
- - Mediastinal neuroendocrine tumors are rare but aggressive cancers that often remain undetected until they reach advanced stages, leading to a poor prognosis.
- - A case study involved a 74-year-old man who underwent successful coronary bypass surgery and simultaneous removal of a large mediastinal tumor found during preoperative checks.
- - Although surgery is the preferred treatment, relapse rates can be high, especially for atypical tumors, yet the patient has been on chemotherapy for 49 months post-operation despite ongoing challenges.
Introduction: Left ventricular pseudoaneurysm is a rare but serious clinicopathologic entity.
Materials And Results: This article describes a case report of 51-year-old man who experienced recurrence of chest pain and dyspnea 4 months later after anterior ST elevation myocardial infarction of first diagonal branch. Anterior basal left ventricular pseudoaneurysm was diagnosed and successful surgical treatment was performed.
Unlabelled: Telomere shortening is well known to be associated with ageing. Age is the most decisive risk factor for age-related macular degeneration (AMD) development. The older the individual, the higher the AMD risk.
View Article and Find Full Text PDFMultisystem Inflammatory Syndrome (MIS) is a rare but increasingly recognized complication of SARS-CoV-2 infection, usually presenting 2 to 6 weeks after the onset of COVID-19 infection symptoms and affecting mainly children. However, there have been reported several cases of a similar multisystem inflammatory syndrome in adults (MIS-A). We describe the case of a previously healthy 28-year-old male who presented with a clinical profile with multiorgan involvement within four weeks after confirmed SARS-CoV-2 infection, suggestive for multisystem inflammatory syndrome (MIS-A).
View Article and Find Full Text PDF. Optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) allowed visualization of retina and choroid to nearly the capillary level; however, the relationship between systemic macrovascular status and retinal microvascular changes is not yet known well. .
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