RISMEAU dataset: Pharmaceuticals and biocides concentrations in urban and agricultural sludge, amended soil and leachate and their environmental impacts.

The RISMEAU project ( - Risks related to residues of pharmaceuticals and biocides, and antimicrobial resistance of human and veterinary origin on the water resources of the 2083 km Arve catchment located in the French Alps) was implanted from 2018 to 2024 on the SIPIBEL observatory. It was devoted to the evaluation of (i) transfers of and processes related to pharmaceutical residues and biocides from both urban sludge and manure spread on fields as fertilisers, and (ii) the environmental impacts of land spreading, in particular the ecotoxicological risks and antimicrobial resistance dissemination. The methodology was based on the physico-chemical, ecotoxicological and antimicrobial resistance (AMR - assessed by molecular biology) characterisation of leachate and soil matrices samples, and focused on organic waste products application at locally representative agronomic rates.

Assessing the chronic toxicity of spreading organic amendments on agricultural soil: Tests on earthworms and plants.

Recycling organic wastes on agricultural soils improves the soil quality, but the environmental and health impact of these organic amendments closely depends on their origins, their bio-physicochemical characteristics and the considered organisms potentially affected. The aim of this study was to assess the potential chronic ecotoxicity of spreading organic amendments on agricultural soils. To do this, we characterized three different organic amendments: sewage sludge from an urban wastewater treatment plant, cow manure and liquid dairy manure.

Assessing the Potential Ecotoxicological Risk of Different Organic Amendments Used in Agriculture: Approach Using Acute Toxicity Tests on Plants and Earthworms.

In Europe, spreading organic wastes to fertilize soils is an alternative commonly used instead of chemical fertilizers. Through their contributions of nutrients and organic matter, these wastes promote plant growth and thus agricultural production. However, these organic amendments can also contain mineral and organic pollutants requiring chemical and ecotoxicological analyses to guarantee their harmlessness on soil and its organisms during spreading.

Role of prey subcellular distribution on the bioaccumulation of yttrium (Y) in the rainbow trout.

Our knowledge of the processes leading to the bioaccumulation of rare earth elements (REE) in aquatic biota is limited. As the contamination of freshwater ecosystems by anthropogenic REE have recently been reported, it becomes increasingly urgent to understand how these metals are transferred to freshwater organisms in order to develop appropriate guidelines. We exposed rainbow trout (Oncorhynchus mykiss) to an REE, yttrium (Y), to either a range of Y-contaminated prey (Daphnia magna) or a range of Y-contaminated water.

Outcomes of kidney transplant recipients admitted to the intensive care unit: a retrospective study of 200 patients.

Background: Risk of over-immunosuppression or immunization may mitigate the overall and long-term renal outcomes of kidney transplant recipients (KTR) admitted to the ICU in the modern era but remain poorly described. Thus, there is an unmet need to better characterize the survival of KTR admitted to the ICU, but also the renal and immunological outcomes of survivors.

Methods: Retrospective observational study that included 200 KTR admitted between 2010 and 2016 to the ICU of a teaching hospital (median age 61 years [IQR 50.