Publications by authors named "Olivier G Maisonet"

Purpose: The optimal local therapy of patients with nodal disease in supraclavicular (SCV), internal mammary nodes (IMN) and level III axilla is not well studied. We aimed to evaluate the outcomes of patients with breast cancer and advanced nodal disease that received a nodal boost.

Methods And Materials: This retrospective study included 79 patients with advanced nodal disease who underwent adjuvant radiation with a nodal boost to the SCV, IMNs, and/or axilla.

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Purpose: To compare heart and lung doses for adjuvant whole breast irradiation (WBI) between radiation plans generated supine with deep inspiratory breath hold (S-DIBH) and prone with free-breathing (P-FB) and examine the effect of breast volume (BV) on dosimetric parameters.

Methods And Materials: Patients with left breast ductal carcinoma in situ or invasive cancer receiving adjuvant WBI were enrolled on a single-institutional prospective protocol. Patients were simulated S-DIBH and P-FB; plans were generated using both scans.

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Article Synopsis
  • - The study compares two whole breast irradiation techniques: deep inspiration breath hold (DIBH) and prone positioning (P-FB), focusing on dosimetry and potential cardiac and lung cancer risks for patients with left-sided breast conditions.
  • - Both techniques showed similar low risks for ischemic heart disease and acute coronary events, but prone positioning had lower estimated lung cancer mortality compared to DIBH.
  • - Prone positioning resulted in a 0.5% absolute decrease in excess lung cancer mortality due to radiation, while both techniques effectively spared the heart from radiation exposure.
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Introduction: The incidence of invasive anal squamous-cell carcinoma in patients with HIV is increasing. We report the outcome after combined chemoradiotherapy for anal squamous-cell carcinoma in HIV-infected individuals.

Methods: Thirty-two HIV-positive patients treated at the St.

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