Intraoperative patellar tracking assessment during image-based robotic-assisted total knee arthroplasty: technical note and reliability study.

Introduction: Restoration of the anterior knee compartment is increasingly studied with the development of personalized surgery. However, evaluating the patellar tracking during the surgery is still subjective and at the surgeon's discretion. This study aimed 1) to describe the assessment of the patellar tracking during robotic-assisted total knee arthroplasty (TKA), 2) to describe a new measurement technique for evaluating the evolution of this patellar tracking, and 3) to assess its reliability and repeatability.

Noise pollution causes parental stress on marine invertebrates, the Giant scallop example.

In marine invertebrates, abiotic stresses on adults can act directly on gametes quality, which impacts phenotype and development success of the offspring. Human activities introduce noise pollution in the marine environment but still few studies on invertebrates have considered the impacts on adult or larval stages separately, and to our knowledge, never investigated the cross-generational effects of anthropogenic noise. This article explores parental effects of pile driving noise associated with the building phase of offshore wind turbines on a coastal invertebrate, Pecten maximus (L.

Biphasic Calcium Phosphate and Activated Carbon Microparticles in a Plasma Clot for Bone Reconstruction and In Situ Drug Delivery: A Feasibility Study.

The development of bone-filling biomaterials capable of delivering in situ bone growth promoters or therapeutic agents is a key area of research. We previously developed a biomaterial constituting biphasic calcium phosphate (BCP) microparticles embedded in an autologous blood or plasma clot, which induced bone-like tissue formation in ectopic sites and mature bone formation in orthotopic sites, in small and large animals. More recently, we showed that activated carbon (AC) fiber cloth is a biocompatible material that can be used, due to its multiscale porosity, as therapeutic drug delivery system.

Trace element variations in mussels' shells from continent to sea: The St. Lawrence system, Canada.

Rare Earth Elements (REE) and several trace elements abundances in mussel's shells collected along the St. Lawrence River, the Estuary, and the Gulf of St. Lawrence (EGSL) reveal coherent chemical variations, with a sharp contrast between freshwater and seawater bivalves.

Quantitative live-cell imaging of Candida albicans escape from immune phagocytes.

Population-level dynamics of host-pathogen interactions can be characterized using quantitative live-cell imaging. Here, we present a protocol for infecting macrophages with the fungal pathogen Candida albicans in vitro and quantitative live-cell imaging of immune and pathogen responses. We describe steps for detailed image analysis and provide resources for quantification of phagocytosis and pathogen escape, as well as macrophage membrane permeabilization and viability.

Effect of neuromuscular injury prevention strategies on injury rates in adolescent males playing sport: a systematic review protocol.

Objective: This review will assess the effectiveness of neuromuscular injury prevention strategies on injury rates among adolescent males playing sports.

Introduction: Adolescent athletes are predisposed to injuries during this period of growth. Growth-related injury risk factors can be mitigated by implementing appropriate neuromuscular injury prevention strategies.

Seasonal lipid dynamics of four Arctic bivalves: Implications for their physiological capacities to cope with future changes in coastal ecosystems.

The Arctic is exposed to unprecedented warming, at least three times higher than the global average, which induces significant melting of the cryosphere. Freshwater inputs from melting glaciers will subsequently affect coastal primary production and organic matter quality. However, due to a lack of basic knowledge on the physiology of Arctic organisms, it remains difficult to understand how these future trophic changes will threaten the long-term survival of benthic species in coastal habitats.

Effects of anthropogenic magnetic fields on the behavior of a major predator of the intertidal and subtidal zones, the velvet crab Necora puber.

With the progress of the offshore renewable energy sector and electrical interconnection projects, a substantial rise in the number of submarine power cables is expected soon. Such cables emit either alternating or direct current magnetic fields whose impact on marine invertebrates is currently unknown and hardly studied. In this context, this study aimed to assess potential short-term exposure (30 min) effects of both alternating and direct magnetic fields of increasing intensity (72-304 μT) on the behavior of the high-ecological value velvet crab (Necora puber).

Pile driving and drilling underwater sounds impact the metamorphosis dynamics of Pecten maximus (L., 1758) larvae.

One of the biggest challenges of the 21st century is to reduce carbon emissions and offshore wind turbines seem to be an efficient solution. However, during the installation phase, high levels of noise are emitted whose impacts remain not well known, particularly on benthic marine invertebrates displaying a bentho-planktonic life-cycle. For one century, larval settlement and subsequent recruitment has been considered as a key topic in ecology as it determines largely population renewal.

The proteasome regulator Rpn4 controls antifungal drug tolerance by coupling protein homeostasis with metabolic responses to drug stress.

Fungal pathogens overcome antifungal drug therapy by classic resistance mechanisms, such as increased efflux or changes to the drug target. However, even when a fungal strain is susceptible, trailing or persistent microbial growth in the presence of an antifungal drug can contribute to therapeutic failure. This trailing growth is caused by adaptive physiological changes that enable the growth of a subpopulation of fungal cells in high drug concentrations, in what is described as drug tolerance.

Outcomes of robotic versus laparoscopic ventral mesh rectopexy for rectal prolapse.

Introduction: Minimally invasive ventral mesh rectopexy is considered the standard of care in the surgical management of rectal prolapse syndromes in fit patients. We aimed to investigate the outcomes after robotic ventral mesh rectopexy (RVR) and compare them with our laparoscopic series (LVR). Additionally, we report the learning curve of RVR.

The core of performance in adolescent cricket pace bowlers: Trunk muscle stability, maybe, but not strength-endurance and thickness.

Background: The trunk connects the upper and lower limbs and transfers energy during movement. Exploring the role of the trunk muscles in bowling performance affords us the opportunity to uncover potential mechanisms to improve bowling performance.

Objectives: To investigate the association between bowling performance and trunk muscle stability, strength-endurance and thickness in adolescent pace bowlers.

The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways.

The egress of Candida hyphae from macrophages facilitates immune evasion, but it also alerts macrophages to infection and triggers inflammation. To better define the mechanisms, here we develop an imaging assay to directly and dynamically quantify hyphal escape and correlate it to macrophage responses. The assay reveals that Candida escapes by using two pore-forming proteins to permeabilize macrophage membranes: the fungal toxin candidalysin and Nlrp3 inflammasome-activated Gasdermin D.

Robotic retromuscular abdominal wall repair using an inverted TEP (iTEP) approach: surgical technique and short-term outcomes.

Purpose: Robotic retromuscular abdominal wall repair (RAWR) for ventral hernias can be performed transabdominal or extraperitoneal by using an enhanced view totally extraperitoneal repair (eTEP). For defects in the meso- or epigastric region, an inverted approach can be used, starting the development of the totally extraperitoneal plane in the suprapubic region and progressing in a caudal-to-cranial direction (inverted TEP, iTEP). The aim of the study is to present the surgical technique and to report the short-term outcomes.