Proteomics and Lipidomics Investigations to Decipher the Behavior of C2c Maky According to Different Culture Modes.

C2c Maky is a free-living amoeba that has demonstrated its ability to inhibit the intracellular multiplication of some strains, which are pathogenic bacteria inhabiting the aquatic environment. The Amoeba, an industry involved in the treatment of microbiological risk in the water and plant protection sectors, has developed a natural biocide based on the property of to manage the proliferation of the pathogen in cooling towers. In axenic liquid medium, amoebas are usually cultivated in adhesion on culture flask.

A New Active Substance Derived from Lyzed C2c Maky Cells to Fight Grapevine Downy Mildew.

Downy mildew of grapevine is one of the most destructive grapevine diseases worldwide. Nowadays, downy mildew control relies almost exclusively on the use of chemical pesticides, including copper products, which are efficient but controversial due to their environmental toxicity. Natural plant protection products have become important solutions in the quest for the sustainable production of food and pest management.

Insight into the Lifestyle of Amoeba during Bioreactor Growth Using Transcriptomics and Proteomics.

C2c maky is a thermophilic free-living amoeba strain that showed ability to eliminate , a pathogenic bacterium living in the aquatic environment. The amoeba industry has proposed the use of as a natural biocide to control proliferation in cooling towers. Here, transcriptomic and proteomic studies were carried out in order to expand knowledge on produced in a bioreactor.

Intracellular Behaviour of Three Strains within Three Amoeba Strains, Including C2c Maky.

is a facultative intracellular pathogen found in aquatic environments as planktonic cells within biofilms and as intracellular parasites of free-living amoebae such as . This pathogen bypasses the elimination mechanism to replicate within amoebae; however, not all amoeba species support the growth of . C2c Maky, a non-pathogenic amoeba, was previously demonstrated to possess the ability to eliminate the strain Paris.