Performance evaluation of an automated electrochemiluminescent calcitonin (CT) immunoassay in diagnosis of medullary thyroid carcinoma.

Objectives: The aim was to evaluate the Elecsys® hCT electrochemiluminescence immunoassay on the immunoanalyser Cobas e411.

Design And Methods: Within-run, between-run imprecision, linearity, recovery after dilution, the high dose hook effect, as well as the stability of calcitonin were examined. A method comparison to an established immunoradiometric assay was executed in 135 routine plasma samples.