Publications by authors named "Olivia Perez"

Article Synopsis
  • Hip osteoarthritis (HOA) is a common joint disease, and recent research is exploring bone-marrow derived stem cell (BM-MSC) therapy as a possible treatment option.
  • A scoping review was conducted to examine the preparation, dosage, and effectiveness of BM-MSC therapy in treating HOA, using guidelines and a comprehensive literature search.
  • The review found that while BM-MSC therapy seems beneficial in reducing pain and improving function in HOA patients, the studies utilized "low-dose" injections, making it difficult to establish a clear relationship between dose and clinical outcomes.
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Pickleball is a popular sport. Also popular is wearable technology usage. Because the validity and reliability of wearable technology during pickleball is unknown, the purpose of this research was to evaluate the ability of common devices to return heart rate and estimated energy expenditure during pickleball activity.

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Recent studies have implicated a crucial role of Hippo signaling in cell fate determination by biomechanical signals. Here we show that mechanical loading triggers the activation of a Hippo-PKCζ-NFκB pathway in chondrocytes, resulting in the expression of NFκB target genes associated with inflammation and matrix degradation. Mechanistically, mechanical loading activates an atypical PKC, PKCζ, which phosphorylates NFκB p65 at Serine 536, stimulating its transcriptional activation.

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The COVID-19 pandemic significantly impacted food behavior choices, including in procurement, preparation, and waste management. Although some of these behavior changes have resulted in positive economic outcomes, such as the growth of employment opportunities for food delivery personnel, others have been deemed environmentally unsustainable, such as the increase in materials used for food packaging. This study examined how the pandemic intensified the negotiations between sustainability and health in food choice behaviors in Hong Kong and demonstrated how contextual and social determinants influenced these behaviors.

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Background: International guidelines recommend quantitative neuromuscular monitoring when administering neuromuscular blocking agents. The train-of-four count is important for determining the depth of block and appropriate reversal agents and doses. However, identifying valid compound motor action potentials (cMAPs) during surgery can be challenging because of low-amplitude signals and an inability to observe motor responses.

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Knee osteoarthritis (KOA) is a degenerative disease resulting from mechanical overload, where direct physical impacts on chondrocytes play a crucial role in disease development by inducing inflammation and extracellular matrix degradation. However, the signaling cascades that sense these physical impacts and induce the pathogenic transcriptional programs of KOA remain to be defined, which hinders the identification of novel therapeutic approaches. Recent studies have implicated a crucial role of Hippo signaling in osteoarthritis.

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Objective: Carpal tunnel syndrome (CTS) is the most common nerve entrapment neuropathy in the USA. In this study, we define anatomical landmarks to assess symptomatic and asymptomatic cohorts with persistent CTS using MRI imaging.

Materials And Methods: Distal vs proximal incomplete release was determined using the distal most aspect of the hook of hamate and the distal wrist crease.

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Background: Tarsal coalition is one of the most common foot and ankle pathologies in children, yet there is no consensus regarding what to interpose after resection. Fibrin glue could be considered, but the literature comparing fibrin glue to other interposition types is sparse. The purpose of this study was to evaluate the effectiveness of fibrin glue for interposition compared with fat graft by analyzing the rate of coalition recurrence and wound complications.

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Background: Bibliometric analysis is a unique tool that can be used to study the characteristics and trends of a given topic. This study aimed to report on the most influential studies concerning revision shoulder arthroplasty research.

Methods: On July 4th, 2022, the Institute of Scientific Information (ISI) Web of Knowledge Database was used to identify articles concerning revision shoulder arthroplasty research.

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Article Synopsis
  • Prolonged opioid use can lead to a condition called opioid-induced hyperalgesia (OIH), where the pain sensitivity increases instead of decreases.
  • A study investigated the role of alternative splicing in genes and how they contribute to OIH, revealing different patterns of gene expression in certain brain regions of mice exposed to chronic morphine.
  • The findings emphasize the importance of understanding specific gene isoforms and regulatory factors involved in OIH to better comprehend the effects of morphine on pain sensitivity.
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Objective: To test the hypotheses that emerging viruses are associated with neurological hospitalizations and that statistical models can be used to predict neurological sequelae from viral infections.

Methods: An ecological study was carried out to observe time trends in the number of hospitalizations with inflammatory polyneuropathy and Guillain-Barré syndrome (GBS) in the state of Rio de Janeiro from 1997 to 2017. Increases in GBS from month to month were assessed using a Farrington test.

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The American Medical Association (AMA) and National Institutes of Health (NIH) currently suggest that health care materials be written at a sixth-grade reading level. Our study investigates the readability of online information on Achilles rupture and reconstruction. , and were queried using advanced search functions of Google, Bing, and Yahoo!.

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