Hypercalcemia is typically associated with primary hyperparathyroidism, malignancy, vitamin D intoxication, and granulomatous disease; however, it can also be associated with a neuroendocrine tumor that secretes vasoactive intestinal polypeptide (VIP). A 74-year-old woman with a history of hypothyroidism and nephrolithiasis presented to her primary care physician with a chief complaint of diarrhea and was found to have mild hypercalcemia. A Hypercalcemia workup was initiated, and the patient was ultimately found to have elevated VIP.
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