Immunostaining as an adjunct to cytology for diagnosis of pancreatic adenocarcinoma.

Background & Aims: Serial analysis of gene expression has helped identify several proteins that are expressed differentially in pancreatic cancer and are highly sensitive and specific for pancreatic adenocarcinoma. We evaluated if the diagnostic accuracy of pancreatic cancer from endoscopic ultrasound (EUS)-fine-needle aspiration (FNA) can be improved by combined evaluation of cytology and immunostaining with these markers.

Methods: This study involved the use of archived specimens from patients treated at Saint Louis University Hospital from 2002 to 2006.

Primary synovial sarcoma.

Purpose: To describe the clinicopathologic and immunohistochemical features and treatment of a rare case of primary synovial sarcoma of the orbit.

Design: Retrospective interventional case report.

Participant: A 14-year-old young man with histologically proven synovial sarcoma of the orbit.