Publications by authors named "Olivia Heutlinger"

Article Synopsis
  • - The study developed a nomogram to predict the likelihood of pelvic lymph node metastases (ypN+) after neoadjuvant chemotherapy in nonmetastatic muscle-invasive bladder cancer patients, finding that ypN+ is linked to worse overall survival.
  • - Data from 6,194 patients were analyzed, revealing that 22.8% of high-risk patients had ypN+, compared to only 8.0% in the low-risk group, with high-risk patients experiencing significantly shorter survival (36.1 vs. 74.0 months).
  • - Key factors contributing to the nomogram included age, time from diagnosis to treatment, and the tumor’s histology and stage, making it a valuable tool for assessing risk
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An increasing body of literature supports the clinical benefit of nutritional assessment and optimization in surgical patients; however, this data has yet to be consolidated in a practical fashion for use by surgeons. In this narrative review, we concisely aggregate emerging data to highlight the role of nutritional optimization as a promising, practical perioperative intervention to reduce complications and improve outcomes in surgical patients. This review of the surgical nutrition literature was conducted via large database review.

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Article Synopsis
  • The study identified factors that delay the start of salvage radiation therapy in prostate cancer patients post-prostatectomy, specifically focusing on PSA levels.
  • It analyzed data from 81 patients treated between 2011 and 2022, noting that insurance type significantly influenced the timing of treatment initiation, with HMO and PPO patients more likely to experience delays.
  • The findings highlight the importance of PSA monitoring and access to timely care, especially for patients with certain insurance plans, suggesting that healthcare policies may impact treatment outcomes.
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BACKGROUND Overdoses on over-the-counter (OTC) drugs are increasing in the United States, which includes widely available non-steroidal anti-inflammatory drugs (NSAIDs) like naproxen. Symptoms of NSAID toxicity are well known and nonspecific, including nausea, vomiting, abdominal pain, and headaches. Extreme cases can present with confusion, seizures, and renal failure.

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Background: We investigated the association between chronic pediatric neurological conditions and the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Methods: This matched retrospective case-control study includes patients (n = 71,656) with chronic complex neurological disorders under 18 years of age, with laboratory-confirmed diagnosis of COVID-19 or a diagnostic code indicating infection or exposure to SARS-CoV-2, from 103 health systems in the United States. The primary outcome was the severity of coronavirus disease 2019 (COVID-19), which was classified as severe (invasive oxygen therapy or death), moderate (noninvasive oxygen therapy), or mild/asymptomatic (no oxygen therapy).

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Background: Minimally invasive surgeries for non-small cell lung cancers (NSCLCs) such as video-assisted thoracoscopic surgeries (VATSs) and robotic-assisted thoracoscopic surgeries (RATSs) have become standard of care for patients needing surgical resection in early stages. The role for neoadjuvant systemic therapy has increased with patients receiving neoadjuvant systemic chemotherapy and immunotherapy. However, there has been some equipoise over the intraoperative and overall outcomes for these patients.

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Importance: Identifying the associations between severe COVID-19 and individual cardiovascular conditions in pediatric patients may inform treatment.

Objective: To assess the association between previous or preexisting cardiovascular conditions and severity of COVID-19 in pediatric patients.

Design, Setting, And Participants: This retrospective cohort study used data from a large, multicenter, electronic health records database in the US.

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