Publications by authors named "Olivia Grubman"

Article Synopsis
  • A universal transvaginal ultrasound (UTVUS) protocol was introduced at an institution to standardize ultrasound practices during the anatomy scan, aiming to improve outcomes like preterm birth and neonatal complications.
  • A retrospective study analyzed 2,118 singleton pregnancies, comparing outcomes between a group that underwent risk-based TVUS (pre group) and a group that received UTVUS (post group), with no significant differences in adverse outcomes such as preterm birth or NICU admissions.
  • The implementation of UTVUS did lead to increased use of vaginal progesterone but ultimately did not demonstrate a reduction in negative pregnancy effects compared to the previous selective ultrasound approach.
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Objective: To assess whether universal use of every-other-day glucose monitoring in patients with gestational diabetes mellitus (GDM) resulted in similar birth weights and medication use and was preferred by the patient compared with traditional daily glucose monitoring.

Methods: This was a noninferiority randomized controlled trial conducted at a single New York City hospital between April 2021 and May 2022. Patients with singleton pregnancies who were diagnosed with GDM after 20 weeks of gestation and had a minimum of 7 days of previous daily blood glucose testing were randomly assigned to test blood glucose values daily or every other day.

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Purpose: The American College of Medical Genetics and Genomics emphasizes a "consistent and equitable approach for offering carrier screening." At our academic center, publicly insured prenatal patients underwent universal expanded carrier screening (ECS) to promote equitable care. The aim of the study was to evaluate rates, time, and barriers to complete ECS.

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Objective: Expanded carrier screening (ECS) is rising in popularity because of its application in a diverse population, its decreasing cost, and efficiency. However, it has traditionally been used to assess fetal risk. The next generation sequencing ECS panel offered at our academic medical center consists of 283 genes associated with hereditary disorders.

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Background: Alkaline phosphatase (ALP) is an enzyme produced by the liver, small intestine, bone, and kidneys as well as the placenta during pregnancy. ALP levels may increase up to twice the normal limit during pregnancy secondary to placental release and fetal bone growth. Rare case reports of extremely elevated levels of ALP during pregnancy have demonstrated possible association with adverse pregnancy outcomes.

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Article Synopsis
  • - A 31-year-old first-time pregnant woman was diagnosed with a silent parvovirus B19 infection during her second trimester, which was linked to an increased nuchal translucency measurement possibly indicating fetal anemia.
  • - Parvovirus B19 can attack red blood cell precursors, leading to serious fetal complications like anemia, hydrops, or even fetal death; however, the mother’s symptoms are typically mild.
  • - After close monitoring and treatment, including amniocentesis and intrauterine transfusion, the patient delivered a healthy baby boy at nearly 38 weeks, suggesting that proper management can lead to successful pregnancy outcomes despite risks from the virus.
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