Fluorescence-Aided Identification Technique (FIT) Improves Tooth Surface Clean-Up after Debonding of Buccal and Lingual Orthodontic Appliances.

The aim of this study was to evaluate the use of fluorescence inducing light to aid the clean-up of tooth surfaces after bracket removal when using buccal or lingual orthodontic appliances. Two full sets of dental arches using extracted human teeth were assembled, with 14 teeth per arch. All teeth were bonded on their buccal and lingual surfaces.

In vitro comparison of the torsional load transfer of various commercially available stainless-steel wires used for fixed retainers in orthodontics.

Objective: To assess the torsional load transfer of various commercially available stainless-steel wires used for fixed retainers.

Design: An in vitro study using a robotic device.

Setting: Department of Pediatric Oral Health and Orthodontics, University of Basel.

Oncogenic drives tumorigenesis in cutaneous squamous cell carcinoma.

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer characterized by increased mortality. Here, we show for the first time that anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase of the insulin receptor superfamily, plays a pivotal role in the pathogenesis of cSCC. Our data demonstrate that the overexpression of the constitutively active, mutated ALK, , is sufficient to initiate the development of cSCC and is 100% penetrant.