Structure-function relationships of the human vertebral endplate.

Background: Although deformation and fracture of the vertebral endplate have been implicated in spinal conditions such as vertebral fracture and disc degeneration, few biomechanical studies of this structure are available. The goal of this study was to quantify the mechanical behavior of the vertebral endplate.

Methods: Eight-five rectangular specimens were dissected from the superior and/or inferior central endplates of human lumbar spine segments L1 to L4.