Publications by authors named "Olivia Bauraind"
As a result of excessive salt loss, cystic fibrosis patients are at risk of dehydration, especially in hot weather. The urinary sodium/creatinine ratio is an easy and noninvasive tool for assessing whether dietary salt intake is adequate, whatever the patient's age. Recently, new reference values have been established, adapted to the patient's age.
View Article and Find Full Text PDFDiagnosis and management of eosinophilic esophagitis in children: An update from the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN).
J Pediatr Gastroenterol Nutr
August 2024
Article Synopsis
- Eosinophilic esophagitis (EoE) is a chronic condition affecting the esophagus, characterized by inflammation and eosinophil infiltration, necessitating updates to existing guidelines due to new medical knowledge.
- A group of pediatric gastroenterologists reviewed recent studies to create 52 statements and 44 recommendations related to EoE, focusing on diagnostics, treatment options, and diet changes from 2014 to 2022.
- The updated guidelines highlight the emergence of biologics for treatment, the potential role of steroids for esophageal strictures, and the importance of addressing quality of life and transitioning patients to adult care.
In evidence-based medicine, N-of-1 trials are increasingly attractive for rare and heterogeneous conditions. A recent French study illustrates this convincingly in the field of cystic fibrosis. A highly effective triple therapy (ETI) is currently available in Europe, which will eventually help the 85 % of Belgian patients carrying at least one copy of the F508del mutation.
View Article and Find Full Text PDFBackground: Bacterial meningitis caused by non-typhoid Salmonella can be a fatal condition which is more common in low and middle-income countries.
Case Presentation: We report the case of a Salmonella meningitis in a Belgian six-month old male infant. The first clinical examination was reassuring, but after a few hours, his general state deteriorated.
At least 80 % of persons with cystic fibrosis are pancreatic insufficient and benefit from daily supplementation with fat-soluble vitamins (ADEK). Magistral formulations offer ideal flexibility for prescriptions tailored to vitamin A, D and E blood levels. However, they expose to human errors, mainly leading to vitamin D intoxication whose clinical features are related to hypercalcaemia.
View Article and Find Full Text PDFArticle Synopsis
- The pEEr registry was created to gather and analyze data on children with eosinophilic esophagitis (EoE) from various centers in Europe and Israel, focusing on phenotypic characteristics.
- A total of 582 children were analyzed, revealing a median diagnosis age of 10.5 years and a common delay in diagnosis, especially in children under 6, with variations in symptoms based on age.
- Older children more frequently experienced dysphagia and food impaction, while younger children showed non-specific symptoms; treatments differed, with many unresponsive patients receiving topical steroids or elimination diets.
Article Synopsis
- - The study evaluated how pediatric (PG) and adult gastroenterologists (AG) in Europe and the UAE diagnose and manage eosinophilic esophagitis (EoE), focusing on their adherence to clinical guidelines.
- - Results showed that PG are more likely to take biopsies and perform endoscopic follow-ups compared to AG; they also prefer elimination diets over steroids as a second-line therapy after proton-pump inhibitors fail.
- - The findings highlight significant practice differences between PG and AG, as well as regional variations across countries, suggesting that educational initiatives could help improve alignment with current guidelines.
Aim: The aim of this study is to determine the prevalence and evolution of anaemia in prospectively followed children and adolescents diagnosed with Crohn's disease (CD).
Methods: The BELCRO registry (inclusion May 2008-April 2010), describing current clinical treatment practice of children diagnosed with CD, provided data on age, height, body mass index (BMI), paediatric Crohn's disease activity index (PCDAI), therapy and haemoglobin (Hb) at diagnosis 12 and 24 months follow-up. Anaemia was defined as Hb < -2 sd, while severe anaemia was defined as Hb < -4 sd.