Publications by authors named "Olivia A Kozel"

Article Synopsis
  • Myelomeningocele (MMC) primarily impacts low-resource regions, especially where there is no mandatory folic acid fortification, but research on its neurosurgical management is concentrated in high-income countries (HICs).
  • A systematic review revealed that while HICs account for a small percentage of global neural tube defect cases, they dominate both authorship and patient representation in the research literature, with minimal contributions from lower-income countries.
  • Findings suggest a significant disparity in MMC research output relative to disease burden, highlighting an urgent need for increased scholarly attention and resource allocation in lower-income countries where MMC cases are more prevalent.
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Background: Rapid prehospital identification of acute ischemic stroke secondary to large vessel occlusions (AIS-LVO) has been successful in triaging patients, but the use of stroke screening scales often varies. This study aims to compare different stroke screening scales for the detection of anterior and posterior circulation AIS-LVO and AIS secondary to medium vessel occlusions (AIS-MeVO).

Methods: We prospectively analyzed stroke alert activations at a comprehensive stroke center between August 1, 2022 and December 31, 2023.

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Article Synopsis
  • The study investigates how effectively neurosurgical prenatal counseling (nPNC) is provided to families considering myelomeningocele (MMC) repair, focusing on the timing and factors influencing decisions on prenatal versus postnatal treatment.
  • Results show that 97% of families accessed nPNC, with 82% of consultations occurring before 24 weeks gestational age, and a significant number faced exclusions from fetal repair.
  • Most families ultimately chose between fetal repair, postnatal repair, or termination, with the main reasons for declining fetal repair being perceived risks and costs.
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Article Synopsis
  • * A 3-year-old boy showed signs of a left CN VI palsy without other neurological problems, and imaging revealed CM1 and a nearby AICA vessel loop affecting the nerve.
  • * The child underwent posterior fossa decompression surgery to relieve potential nerve compression, leading to complete resolution of his symptoms post-operatively.
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Background: Spinal cord stimulation (SCS) consists of the implantation of neuromodulatory devices in the spinal cord to treat refractory neuropathic pain. Although SCS technology has been proven of immense clinical benefit, complications remain including refractory pain, infection risk, and electrode migration or displacement. Till date, there are minimal reports of allergic side effects following SCS implantation.

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Background: Spinal cord stimulation (SCS) involves the utilization of an implantable neurostimulation device, stereotypically used in the treatment of patients with chronic neuropathic pain. While these devices have been shown to have significant clinical benefits, there have also been documented potential complications, including the risk of infection, fractured electrodes, electrode migration, and lack of symptom improvement. In addition, there has been minimal documentation on gastrointestinal (GI) side effects after SCS implantation.

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Article Synopsis
  • Advances in technologies and the 2011 MOMS trial have shifted myelomeningocele repair (MMCr) practices, yet postnatal procedures are still common due to factors like prenatal diagnosis limitations and personal preference.
  • A study analyzing postnatal MMCr trends from 2000-2019 found a gradual decline in operations after 2011, with increasing prevalence among Medicaid and low-income patients, highlighting ongoing disparities.
  • By 2019, there was a convergence in race/ethnicity-adjusted rates, with no significant change in mortality rates or lower post-MOMS shunting during the same admission.
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