Investigating the importance of selected surface-exposed loops in HpuB for hemoglobin binding and utilization by .

is the etiological agent of the sexually transmitted infection gonorrhea. The pathogen is a global health challenge since no protective immunity results from infection, and far fewer treatment options are available with increasing antimicrobial resistance. With no efficacious vaccines, researchers are exploring new targets for vaccine development and innovative therapeutics.

Investigating the importance of surface exposed loops in the gonococcal HpuB transporter for hemoglobin binding and utilization.

is the etiological agent of the sexually-transmitted infection gonorrhea and a global health challenge since no protective immunity results from infection and far fewer treatment options are available with increasing antimicrobial resistance. With no efficacious vaccines, researchers are exploring new targets for vaccine development and innovative therapeutics. The outer membrane TonB-dependent transporters (TdTs) produced by are considered promising antigen targets as they are highly conserved and play crucial roles in overcoming nutritional immunity.