Influence of factors regulating bone formation and remodeling on bone quality in osteonecrosis of the femoral head.

Osteonecrosis of the femoral head (ONFH) usually affects young individuals and has a major impact on lifestyle. Notably, the pathogenetic mechanisms of osteonecrosis are unresolved and no effective treatment exists. The objective of this study was to assess the gene expression levels of factors regulating bone formation and remodeling (bone morphogenetic protein [BMP]-2, BMP-7, Runx2, osteocalcin, osteoprotegerin [OPG]) in patients with ONFH and to compare them to those of patients with primary osteoarthritis (OA).

Computer-assisted cannulated screw fixation for slipped capital femoral epiphysis.

In slipped capital femoral epiphysis (SCFE), cannulated screw fixation is a standard procedure. The aim of this study was to investigate the feasibility of a fluoroscopy-supported navigation system for screw fixation in SCFE. Using a fluoroscopy-enhanced navigation system, a cannulated screw fixation was performed in seven hips of four patients.