Publications by authors named "Oliver Troy"
Proc Natl Acad Sci U S A
April 2023
Article Synopsis
- Disrupted circadian rhythms are linked to various neuropsychiatric disorders, with adrenal glucocorticoids playing a significant role in regulating processes like metabolism, immune response, mood, and cognitive functions.
- In a study with rats, researchers found that corticosteroid treatment affected circadian regulation in the hippocampus, which is crucial for memory and learning by linking gene regulation to synaptic plasticity.
- The disruption of the normal circadian pattern due to corticosteroid exposure caused misalignment with natural light cues, resulting in memory impairments, providing insights into how synthetic corticosteroid treatments may lead to cognitive deficits in patients.
