Time course and local distribution of skin exposure of hand and fingers from [68Ga]Ga-DOTA-NOC synthesis using a self-shielded module.

Aim:  The study examined the local dose distribution as well as the time course of skin exposure of hand and fingers from [Ga]Ga-DOTA-NOC synthesis using a self-shielded synthesis module.

Methods:  A compact calibrated electronic dosimeter (ED) with a miniaturized probe was used for real-time measurements of skin dose equivalent H (0.07) (reference point: left and right index finger).

Extraction of Radium by haemodialysis after treatment of metastatic castration-resistant prostate cancer.

Aim: Radium-dichloride (Ra) administration is an upcoming therapeutic option in patients with castration-resistant metastatic prostate cancer (mCRPC), whose renal and faecal excretion of Ra has been primarily estimated from data of a phase-I clinical trial in patients with normal renal function. In the rare case of concomitant renal insufficiency requiring haemodialysis (HD), an estimation of the contamination of dialysate would be beneficial.

Methods: The excretion of Ra and its concentration in the dialysate in a patient with mCRPC and end-stage renal disease was examined for six consecutive treatment cycles.