Publications by authors named "Oliver L Steiner"
Chronic inflammatory demyelinating polyneuropathy (CIDP) compromises functions of the peripheral nervous system (PNS). Recently, however, symptoms such as cognitive deficits, visual dysfunction and circadian disorders were reported, compatible with additional involvement of the central nervous system (CNS) in CIDP. Against this background, we were interested in the functional state of melanopsin-expressing retinal ganglion cells (mRGCs) as a potential biomarker for sleep-wake abnormalities and CNS involvement in CIDP.
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- Neurodegenerative diseases exhibit retinal abnormalities, and chromatic pupillometry is a technique to assess the functionality of retinal photoreceptors, specifically in Alzheimer's and Parkinson's diseases.
- This meta-analysis examined existing literature involving 42 Alzheimer's patients and 66 Parkinson's patients, finding no significant impairment in retinal response for Alzheimer's but a notable deficit in Parkinson's.
- The findings suggest chromatic pupillometry is effective for assessing retinal issues in Parkinson's but not Alzheimer's, emphasizing the need for further studies to explore factors like treatment effects and stimulation methods.