High-Frequency Ultrasound for Detecting Periodontal Inflammation: A Preclinical Diagnostic Accuracy Study.

Aim: Ultrasonography (US) has shown accuracy in imaging healthy periodontium. This study aims to evaluate the feasibility and accuracy of US for estimating dimensions of inflamed periodontium induced by ligature and bacteria.

Methods: Periodontal tissues of maxillary as well as mandibular premolars and molars in six female mini pigs were treated with ligature and three strains of bacteria for 4-10 weeks.

Quantitative Ultrasound for Periodontal Soft Tissue Characterization.

Objective: Periodontal diseases are a spectrum of inflammatory diseases that affect 45.9% of adults aged ≥30 years in the United States Current standard of care in clinics for the assessment of oral soft tissue inflammation is bleeding on probing,which is invasive, subjective and semi-qualitative. Quantitative ultrasound (QUS) has shown promising results in the non-invasive quantitative characterization of various soft tissues; however, it has not been used in clinical periodontics.

Safety, Ergonomics and Patient Centered Point-of-Care Ultrasound.

Ultrasound imaging is a safe diagnostic tool that has become ubiquitous, in part due to its portability, effectiveness, and safety record. The latter is aided be adherence to regulatory limits, safety guidelines, and the "as low as reasonably achievable" principle. Operators receive feedback on potential tissue heating and mechanical effects through output display standard that shows the thermal index and mechanical index.

A Life-Size Three-Dimensional Phantom for Periodontal Imaging Development and Treatment-Planning.

Rationale And Objectives: This study aims to (1) describe a periodontal and implant ultrasound imaging phantom designed for training of common periodontal and peri-implant soft- and hard-tissue deficiencies, and (2) detail the specific anatomical phantom features and showcase imaging data obtained from intraoral scans, cone beam computed tomography (CBCT) as well as ultrasound.

Materials And Methods: A prototype, full-sized, three-dimensional (3D), periodontal ultrasound phantom was created. To mimic periodontal and peri-implant soft-tissue, a phantom material similar to soft-tissue was attached.

Ultrasound Characterization of Oral Soft Tissues Using the Burr Speckle Model.

Periodontal (gum) diseases, reportedly affect 4 out of 10 adults 30 years of age or older in the USA. The standard of care for clinical assessments of these diseases is bleeding on probing, which is invasive, subjective and semi-qualitative. Thus, research on proposing alternative noninvasive modalities for clinical assessments of periodontal tissues is crucial.

Use of High-Frequency Ultrasound for the Correlation of Epithelial Rete Peg Variation.

Objective: Rete pegs are projections of the oral epithelium into connective tissue. Their dimensions change during pathological conditions and may correlate with wound-healing status. Non-invasive, high-frequency ultrasound (US) may be able to capture these changes and aid in early detection of histopathological changes.

Intraoral ultrasonography image registration for evaluation of partial edentulous ridge: A methodology and validation study.

Objectives: Ultrasound (US) reveals details for diagnosing soft- and hard-tissue dimensions around teeth, implants, and the edentulous ridge, not seen in 2D radiographs. Co-registering free-hand US scans with other 3D modalities presents reliability challenges. This study first aims to develop and validate a registration method to longitudinally reproduce US images of the jawbone on a simulator.

Sonography in the diagnosis of peri-implant bone defects: An in vitro study on native human mandibles.

Aim: The aim of this study on native human cadavers was to compare clinical, sonographic, and radiological measurements of fenestrations, dehiscences, and 3-wall bone defects on implants.

Materials And Methods: The examination was carried out on five human mandibles. After the insertion of 27 implants, dehiscences (n = 14), fenestrations (n = 7) and 3-wall bone defects (n = 6) were prepared in a standardized manner.

Ultrasound-based jawbone surface quality evaluation after alveolar ridge preservation.

Background: Bone readiness for implant placement is typically evaluated by bone quality/density on 2-dimensional radiographs and cone beam computed tomography at an arbitrary time between 3 and 6 months after tooth extraction and alveolar ridge preservation (ARP). The aim of this study is to investigate if high-frequency ultrasound (US) can classify bone readiness in humans, using micro-CT as a reference standard to obtain bone mineral density (BMD) and bone volume fraction (BVTV) of healed sockets receiving ARP in humans.

Methods: A total of 27 bone cores were harvested during the implant surgery from 24 patients who received prior extraction with ARP.

Color Flow Ultrasound Spatial Sampling Beam Density for Partial Volume-Corrected Three-Dimensional Volume Flow (3DVF): Theory, Simulation, and Experiment.

Objective: The purpose of this study was to quantify the accuracy of partial volume-corrected three-dimensional volume flow (3DVF) measurements as a function of spatial sampling beam density using carefully-designed parametric analyses in order to inform the target applications of 3DVF.

Methods: Experimental investigations employed a mechanically-swept curvilinear ultrasound array to acquire 3D color flow (6.3 MHz) images in flow phantoms consisting of four lumen diameters (6.

Quantitative Ultrasound for Periodontal Soft Tissue Characterization.

Periodontal diseases affect 45.9\% of adults aged 30 or older in the United States. Current diagnostic methods for clinical assessment of these diseases are visual examination and bleeding on probing that are subjective, qualitative, and/or invasive.

Comment on Barbieri et al. Umbilical Vein Blood Flow in Uncomplicated Pregnancies: Systematic Review of Available Reference Charts and Comparison with a New Cohort. 2023, , 3132.

We would like to comment on the systemic review article published in the Journal of Clinical Medicine by Barbieri et al [...

Measurement of Cerebral Metabolism Under Non-Chronic Hemodynamic Conditions.

Background: Blood flow to the brain is a critical physiological function and is useful to monitor in critical care settings. Despite that, a surrogate is most likely measured instead of actual blood flow. Such surrogates include velocity measurements in the carotid artery and systemic blood pressure, even though true blood flow can actually be obtained using MRI and other modalities.

Doppler ultrasonographic evaluation of tissue revascularization following connective tissue graft at implant sites.

Aim: To assess the Doppler ultrasonographic tissue perfusion at dental implant sites augmented with connective tissue graft (CTG) using coronally advanced flap (CAF) or tunnel technique (TUN).

Materials And Methods: Twenty-eight patients presenting with isolated healthy peri-implant soft-tissue dehiscence (PSTD) were included in this randomized clinical trial. PSTDs were treated with either CAF + CTG or TUN + CTG.

Ultrasonography-Derived Elasticity Estimation of Live Porcine Oral Mucosa.

Objectives: To investigate the biomechanical properties of porcine oral tissues with in vivo ultrasonography and to compare the difference between oral alveolar mucosa and gingival tissue concerning compressional and tensile mechanical strain.

Materials And Methods: Sinclair minipigs (6 females and 4 males, 6 to 18 months of age) were anesthetized for ultrasonography. In vivo high-frequency tissue harmonic ultrasound (12/24 MHz) cine-loops were obtained while inducing mechanical tissue stress (0 to 1 N).

A Narrative Review on Oral Mucosa Biomechanics and Clinical Implications of Periodontal and Implant-Related Regenerative Procedures.

Healing outcomes of periodontal and implant-related regenerative procedures are closely related to wound stability, which is partially determined by biomechanical properties and behaviors of oral mu- cosal tissues. Studies on soft tissue behavior under biomechanical forces in oral regeneration models are scarce. Thus, this review aims to (1) contrast the microstructural differences between the attached gingiva (AM) and lining (LM) mucosa; (2) evaluate biomechanical behaviors of the two mucosal types; and (3) relate residual flap tension to the prevalence of wound opening after regenerative procedures.

Real-time spatiotemporal characterization of mechanics and sonoporation of acoustic droplet vaporization in acoustically responsive scaffolds.

Phase-shift droplets provide a flexible and dynamic platform for therapeutic and diagnostic applications of ultrasound. The spatiotemporal response of phase-shift droplets to focused ultrasound, via the mechanism termed acoustic droplet vaporization (ADV), can generate a range of bioeffects. Although ADV has been used widely in theranostic applications, ADV-induced bioeffects are understudied.

Placental assessment using spectral analysis of the envelope of umbilical venous waveforms in sheep.

Introduction: This study was designed to test the efficacy of an ultrasound flow measurement method to evaluate placental function in a hyperandrogenic sheep model that produces placental morphologic changes and an intrauterine growth restriction (IUGR) phenotype.

Materials And Methods: Pregnant ewes were assigned randomly between control (n = 12) and testosterone-treatment (T-treated, n = 22) groups. The T-treated group was injected twice weekly intramuscularly (IM) with 100 mg testosterone propionate.

Coronally Advanced Flap with Xenogeneic Collagen Matrix for the Treatment of Gingival Recessions at Sites Presenting with Cervical Restorations or Noncarious Cervical Lesions: A Clinical and Ultrasonographic Study.

The aim of this prospective study was to evaluate the efficacy of a cross-linked xenogeneic volume-stable collagen matrix (CCM) in treating gingival recessions (GRs) at teeth presenting with cervical restorations or noncarious cervical lesions (NCCLs). Fifteen patients with esthetic concerns for multiple sites with GRs and cervical restorations were consecutively enrolled. The sites were treated with a coronally advanced flap (CAF) design in combination with a CCM.

Preliminary Experience in Transducer Preparation for Intraoral Imaging.

Intraoral scanning must meet a stringent infection control standard because of contact with the oral mucosa. A preparation protocol is thus presented for increased inquiries about intraoral scanning requirements. Materials required for such a preparation include: a single-use bubble-free gel packet, a gel standoff pad, and a transducer probe cover.

Coronally advanced flap versus tunnel technique for the treatment of peri-implant soft tissue dehiscences with the connective tissue graft: A randomized, controlled clinical trial.

Aim: To evaluate the efficacy of coronally advanced flap (CAF) versus tunnel technique (TUN) in covering isolated mid-facial peri-implant soft tissue dehiscences (PSTDs).

Materials And Methods: Twenty-eight participants presenting with isolated non-molar implants exhibiting PSTDs were enrolled and randomized to receive either CAF or TUN, both with a connective tissue graft (CTG). The primary outcome of the study was the percentage of mean PSTD coverage at 12 months.

Overview of Ultrasound in Dentistry for Advancing Research Methodology and Patient Care Quality with Emphasis on Periodontal/Peri-implant Applications.

Background: Ultrasound is a non-invasive, cross-sectional imaging technique emerging in dentistry. It is an adjunct tool for diagnosing pathologies in the oral cavity that overcomes some limitations of current methodologies, including direct clinical examination, 2D radiographs, and cone beam computerized tomography. Increasing demand for soft tissue imaging has led to continuous improvements on transducer miniaturization and spatial resolution.