Histamine Receptor 1 and 2 Antagonists Alter Biodistribution of Radioiodine.

Unlabelled: Nuclear medicine technology assumes responsibility for examination-specific patient preparation procedures. This requires a clear understanding of the possible effects of medications on the outcome of examinations. There is evidence that common over-the-counter drugs, histamine 1 (H1) and histamine 2 (H2) receptor blockers and proton pump inhibitors, may directly or indirectly affect thyroid function.

The alpha- and beta-epoxides of 3beta-acetoxy-5alpha-lanost-9(11)-en-7-one.

The structures of 3beta-acetoxy-9alpha,11alpha-epoxy-5alpha-lanost-9(11)-en-7-one and 3beta-acetoxy-9beta,11beta-epoxy-5alpha-lanost-9(11)-en-7-one, C(32)H(52)O(4), differ in their respective substituted cyclohexanone rings but adopt similar conformations in the other three rings. In both of the crystal structures, weak intermolecular C-H..

18-Deoxy-13beta,14-dihydrolycoctam: the lycoctamone rearrangement confirmed.

The structure of the title compound, C23H35NO4, contains a unique pentacyclic ring system wherein one cyclohexyl ring adopts a chair conformation, two cyclohexyl rings are in boat conformations, and a six-membered heterocyclic ring and a cyclopentyl ring are in envelope conformations. The structures of the lycoctamones, alpha,beta-unsaturated aldehydes produced by acid-catalyzed degradation of lactams of lycoctonine-type alkaloids, previously deduced from the results of extensive chemical investigations have been proven to be correct by the determination of the crystal structure of this compound.

Implications of the Cattell-Horn-Carroll theory on ethnic differences in IQ.

The Cattell-Horn-Carroll theory of intelligence and the Spearman-Jensen hypothesis were applied to help interpret mean IQ differences among ethnic groups. The Cattell-Horn-Carroll theory classifies cognitive abilities on three strata, which differ by magnitude of generality including specific, broad, and general abilities. The Spearman-Jensen hypothesis advances the belief that mean IQ differences between African Americans and Euro-Americans occur as a function of the test's g loadings.

Generating CTLs against the subdominant Epstein-Barr virus LMP1 antigen for the adoptive immunotherapy of EBV-associated malignancies.

The Epstein-Barr virus (EBV)-encoded LMP1 protein is expressed in EBV-positive Hodgkin disease and is a potential target for cytotoxic T-lymphocyte (CTL) therapy. However, the LMP1-specific CTL frequency is low, and so far the generation of LMP1-specific CTLs has required T-cell cloning. The toxicity of LMP1 has prevented the use of dendritic cells (DCs) for CTL stimulation, and we reasoned that an inactive, nontoxic LMP1 mutant (DeltaLMP1) could be expressed in DCs and would enable the activation and expansion of polyclonal LMP1-specific CTLs.