Publications by authors named "Oliver C Kiersnowski"
Purpose: Data for QSM are typically acquired using multi-echo 3D gradient echo (GRE), but EPI can be used to accelerate QSM and provide shorter acquisition times. So far, EPI-QSM has been limited to single-echo acquisitions, which, for 3D GRE, are known to be less accurate than multi-echo sequences. Therefore, we compared single-echo and multi-echo EPI-QSM reconstructions across a range of parallel imaging and multiband acceleration factors.
View Article and Find Full Text PDFTemporal lobe epilepsy (TLE) is associated with widespread brain alterations. Using quantitative susceptibility mapping (QSM) alongside transverse relaxation rate ( ), we investigated regional brain susceptibility changes in 36 patients with left-sided (LTLE) or right-sided TLE (RTLE) secondary to hippocampal sclerosis, and 27 healthy controls (HC). We compared three susceptibility calculation methods to ensure image quality.
View Article and Find Full Text PDFArticle Synopsis
- Quantitative susceptibility mapping (QSM) is increasingly used in clinical research, but its accuracy can be affected by oblique image acquisition, which isn't well understood.
- The study analyzed the impact of oblique acquisition on QSM by testing different tilt-correction methods using simulations and data from healthy volunteers.
- Results showed that aligning images with the main magnetic field direction before processing steps, particularly after phase unwrapping and before background field removal, is crucial for accurate QSM, and the researchers provided open-source code for tilt correction.*