N-(levodopa) chitosan derivative based on click chemistry shows biological functionality in brain cells.

Objective: To develop N-(levodopa) chitosan derivatives through click chemistry to study their effect in brain cells. This study presents a proof-of-concept that macromolecules such as N-(Levodopa) chitosan derivatives traverse brain cell membranes and induce biomedical functionalities.

Methods: Through click chemistry, we developed N-(levodopa) chitosan derivatives.