Publications by authors named "Olha S Yarmolenko"
Objective: The aim: Determination of morphological features of reparative regeneration of diaphysis defect of long tubular bones under the influence of antitumor chemotherapeutics in a model experiment.
Patients And Methods: Materials and methods: 96 white nonlinear rats after application of the perforated defect of the femur were administered the appropriate antitumor drug (doxorubicin, 5-fluorouracil, methotrexate) three times with an interval of 21 days. Morphological features of bone tissue formation and remodeling in the regenerate area were studied using histological and morphometric methods.
Objective: The aim: To evaluate morphological changes in long tubular bones of mature rats under the influence of experimental hyperglycemia.
Patients And Methods: Materials and methods: The study was conducted on 140 nonlinear white male rats divided into two groups. The experimental group included rats that were introduced into a state of hyperglycemia by a single intraperitoneal injection of an alloxan dihydrate solution at a dose of 150 mg / kg body weight in 0.