Investigation of Effect of the Colistin Loading Dosage on the clinical, Microbiological, and Laboratory Results in Ventilator-Associated Pneumonia /Pneumonia.

Materials And Methods: Adult patients administered colistin with and without LD for MDR VAP/pneumonia in intensive care units (ICUs) in a tertiary teaching hospital between 1 January 2018 and 31 December 2019 were included in this retrospective cohort study. The primary endpoint was an assessment of clinical and microbiological success between treatment groups. Secondary endpoints included 14- and 30-day mortality and development of nephrotoxicity.