[Evaluation of ganglion cells function with PERG test in normal tension glaucoma patients].

Purpose: To evaluate bioelectrical function of inner retinal layers measured by PERG in normal tension glaucoma.

Patients And Methods: In 50 eyes of 30 patients with normal tension glaucoma the following examinations were performed: history, routine ophthalmic examination, standard static perimetry and pattern ERG test.

Results: The most frequent abnormalities were incorrect N95/P50 amplitude ratio and increase latency of N95-wave.

[Electrophysiological tests in early and differential diagnosis of some hereditary retinal and optic nerve diseases].

Purpose: The goal of our study was to determine the value of electrophysiological tests in early and differential diagnosis of some hereditary retinal and optic nerve diseases.

Material And Methods: Review article on the basis of own experiences and results of another authors concerning to EOG, ERG, PERG, MfERG and VEP tests in evaluation of hereditary, stationary and progressive retinal diseases, as well as optic nerve diseases.

Results: Electrophysiological tests can be abnormal even in patients without fundus changes seen in routine ophthalmological examination.

Retinal dysfunction in eyes of patients with BRCA1 gene mutation.

Purpose: To assess the retinal function in BRCA1 gene mutation carriers.

Material And Methods: Thirty unaffected patients (60 eyes) with constitutional BRCA1 gene mutation were studied. Flash ERG recordings were performed in accordance with the International Society for Clinical Electrophysiology of Vision (ISCEV) standards.

[Ophthalmological tests value in detection of the optic neuropathy associated with pituitary tumours].

Purpose: To evaluate the value of ophthalmological tests in detection of the optic neuropathy associated with pituitary tumours.

Material And Methods: 38 patients with pituitary tumours in 21-73 years old, were examined. Routine ophthalmological examination, kinetic and static perimetry (screening test, "white-on-white" and "blue-on-yellow") and PVEP were performed.

[Localization and clinical characteristics of the ocular metastases of solid extraocular tumours].

Localization and clinical characteristics of the ocular metastases of solid tumours are presented. Choroid is the most common localization site of these metastases, however they may involve each ocular structure. In the most cases they are diagnosed in patients with earlier recognized cancer, but in 12-40% of the patients ocular metastasis is a first sign of the neoplasm.

[Ocular metastases of solid extraocular tumors. Frequency of ocular metastases and localization of the primary tumors].

The aim of this paper is, to characterize ocular metastases of solid extraocular tumors and analyze the frequency and localization of their primary sites, according to literature data of 1967-2002 years. The most common source of this metastases are breast, lung and prostate cancers in adults and neuroblastoma in children. Practically used diagnostic ways of ocular metastases in many cases omit histopathology investigation and for this reason in some cases, particularly with coexistence of hereditary cancer predisposition, second primary tumors may be misdiagnosed, as the distant--time ocular metastases.

Supernormal electro-oculograms in patients with neurofibromatosis type 1.

Purpose: To asses the retinal pigment epithelium (RPE) function measured by EOG testing in patients with neurofibromatosis type 1 (NF-1). Our preliminary EOG results suggested dysfunction of the RPE in individuals with NF-1. In order to confirm our initial results we performed EOG examination on a larger group of NF-1 patients.

Electro-oculographic and electroretinographic studies in HNPCC gene mutation carriers.

Purpose: To assess retinal function in HNPCC gene mutation carriers.

Patients: 19 carriers (38 eyes) of HNPCC genes and controls.

Methods: Electro-oculogram, standard flash electroretinogram and pattern electroretinogram (PERG) recordings were performed.

Retinal function in the von Hippel-Lindau disease.

Purpose: To assess the retinal function in patients with von Hippel-Lindau disease (VHL).

Patients: Studies were undertaken in 12 patients (17 eyes) with detected VHL gene mutation and 12 normal healthy controls (17 eyes).

Methods: Pattern ERG (PERG), standard flash electroretinogram (ERG) recordings were performed in accordance with the International Society for Clinical Electrophysiology of Vision (ISCEV) standards.

Electroretinographic changes in eyes of patients with BRCA1 gene mutation.

Aim: To assess the retinal function in BRCA1 gene mutation carriers and to evaluate the clinical significance of its potential alterations.

Patients And Methods: Flash electroretinogram (ERG) was studied in 15 unaffected patients (30 eyes) with constitutional BRCA1 gene mutation. Routine ophthalmological examination was additionally performed in the oldest, unaffected 15 patients and in 15 breast cancer patients being carriers of BRCA1 mutation.

[Use of applicator AMO PhacoFlex II SofTip Insertion System in cataract surgery with IOL implantation].

Purpose: To evaluate the clinical use of the unfolder in cataract surgery with foldable IOL implantation.

Material And Method: Forty eyes of 40 patients were analysed. In all patients cataract phacoemulsification was performed.

Electroretinographic changes in the inner retinal layers of the retained eyes of patients with sporadic unilateral retinoblastoma.

Purpose: Examination of retinal function as measured by flash electroretinogram (ERG) including oscillatory potentials (OPs) and pattern electroretinogram (PERG) in a series of patients with unilateral sporadic retinoblastoma.

Patients: Studies were undertaken in the retained eye (without clinical evidence of retinoblastoma) of 13 patients with sporadic unilateral retinoblastoma and in 13 healthy controls.

Methods: Standard flash ERG including scotopic OPs and PERG recordings were performed in accordance with the International Society for Clinical Electrophysiology of Vision (ISCEV) standards.