Threshold values of antibodies to estrogen, progesteron and benzo [a] pyrene as a risk factor for the development of endometriosis.

Objectives: The objective of the study was to determine the level of antibodies (AB) of Ig classes A and G to estradiol (E2), progesterone (P) and benzo [a] pyrene (Bp) in patients with endometriosis of various severity and estimate their threshold values as a risk factor for the development of endometriosis.

Methods: A retrospective case-control study was performed. The study involved 200 women.

Specific Features of Ethnic Identity in the Regions with Varying Degrees of Ethnic Diversity.

Ethnic diversity describes the plurality of ethnicities within a group of people coexisting in one territory. The permanent presence of other cultures' representatives can trigger a sense of jeopardy; a feeling that the prevailing way of life, its norms, and its values are challenged by strangers, which results in hostility to ethnic minorities living in the same territory. In this context, the study aimed at investigating specific features of the individual's ethnic identity determined by the degree of the ethnic diversity of their living environment is of relevance.

Adenomyosis: genetics of estrogen metabolism.

Background To analyze the allelic variants of genes of enzymes involved in estrogen metabolism: CYP1A1, CYP1A2, CYP19 and SULT1A1 using polymerase chain reaction-restriction fragment length polymorphism-restriction fragment length polymorphism (PCR-RFLP) analysis of women with histologically confirmed adenomyosis and women without proliferative diseases of pelvic organs was performed. We studied the following polymorphisms: CYP1A1 M1, T264 → C transition in the 3'-noncoding region; CYP1A2*1F, C734 → A transversion in CYP1A2 gene; C → T transition (Arg264Cys) in exon 7 of CYP19; SULT1A1*2, G638 → A transition (Arg213His) in the SULT1A1 gene. Materials and methods The study included 804 patients.