Determining Split Renal Function in Children With Ureteropelvic Junction Stenosis: Technetium-99m Mercaptoacetyltriglycine (Tc-99m MAG-3) or Technetium-99m Dimercaptosuccinic Acid (Tc-99m DMSA)?

Background Ureteropelvic junction stenosis (UPJS) is the most common cause of clinically significant antenatal hydronephrosis. We compared separate renal function results obtained using technetium-99m-mercaptoacetyltriglycine (Tc-99m MAG-3) and technetium-99m-dimercaptosuccinic acid (Tc-99m DMSA) in pediatric patients with UPJS to evaluate the adequacy of Tc-99m MAG-3 scintigraphy and the necessity of additional Tc-99m DMSA scintigraphy during follow-up. Methodology Patients diagnosed with hydronephrosis in the Pediatric Nephrology Department of Pamukkale University Faculty of Medicine over a period of 10 years (2012-2022) were evaluated retrospectively.

Confirmation of PSMA expression measured on [68Ga]Ga-PSMA PET/CT by immunohistochemistry in prostate adenocarcinoma.

Background: Our aim is to determine the accuracy of [68Ga]Ga-PSMA PET/CT in showing PSMA expression in primary prostate cancer and to investigate the relationship between SUVmax and immunohistochemical PSMA expression, Gleason score, and PSA value.

Material And Methods: We retrospectively analyzed 66 male patients who were diagnosed with primary prostate adenocarcinoma, underwent pre-treatment [68Ga]Ga-PSMA PET/CT examination for staging, and performed radical prostatectomy between March 2018-August 2020. Immunohistochemical staining was applied to the radical prostatectomy specimens of all patients to detect PSMA expression.

A New Buffer for Gallium-68 Labeling Suitable for use in Nuclear Medicine; Triethanolamine (TEA).

Background: Radiopharmaceuticals labeled with [Ga] from positron emission tomography (PET) radionuclides are utilized in nuclear medicine for non-invasive in vivo molecular imaging. Buffer solutions for radiolabeling play an important role as choosing the right buffer for the reaction helps to obtain high yield radiopharmaceuticals. Zwitterionic organic buffer 4-(2- hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), sodium acetate (CHCOONa), sodium bicarbonate (NaHCO) buffers are widely used for labeling of peptides with [Ga]Cl.

Role of F-18 FDG PET/CT in Predicting Response to Neoadjuvant Chemotherapy in Invasive Ductal Breast Cancer.

Objective: The role of baseline and post-treatment standardized uptake value (SUV) values in predicting pathological response in patients with breast cancer after neoadjuvant chemotherapy (NAC).

Materials And Methods: Thirty patients with invasive ductal breast cancer were included in this retrospective study. F-18 fluorodeoxyglucose (FDG) positron emission tomography/computerized tomography (PET/CT) examinations were performed before and after NAC.

Relationships of F-FDG uptake by primary tumors with prognostic factors and molecular subtype in ductal breast cancer.

Objectives: In this study, we aimed to investigate the correlation between SUVmax of primary tumor and prognostic factors/molecular subtype in ductal breast cancer patients.

Materials And Methods: We retrospectively reviewed 150 female patients with pathologically proven invasive ductal breast cancer from January 2015 to October 2019 who underwent F-FDG PET/CT for initial staging. Histopathological prognostic features of the primary tumor (histological grade, hormone receptor status, Ki-67 index, vb.

Can PET/CT be used more effectively in pleural effusion evaluation?

Purpose: Sometimes, characterization of pleural effusion (PE) can be challenging especially in patients whom invasive procedures/recurrent invasive procedures cannot be performed. The main purpose of the study is to answer this question, Can F-FDG-PET/CT contribute to reduction in the number of invasive procedures or patients undergoing to invasive procedures? Results may increase the effectiveness of patient management by facilitating clinical decision-making, especially in patients who cannot undergo invasive/recurrent invasive procedures.

Methods: Sixty-seven patients' F-FDG-PET/CT, pleural fluid cytologies (PFCs) and, if any, pleural biopsies were re-assessed.

Comparison of Radiochemical and Chemical Impurities in Liquid Wastes of Two Different Ge/Ga Generators used in Nuclear Medicine PET Chemistry.

Objectives: Germanium-68/gallium-68 (Ge/Ga) generator eluate contains a number of metal cations that can compete with GaCl, reducing specific radioactivity. The first step in peptide labeling with GaCl is to remove Ge and several other metals with a long half-life. In this purification step, the elution residue that is passed through the cartridge is collected in glass waste bottles.

Examination of metallic impurities of 68Ge/68Ga generators used for radioactive labeling of peptides in clinical PET applications.

Background/aim: Especially suitable for PET due to its nuclear physical and radiochemical properties, the positron emitter Gallium-68 (Ga) occurs by electron capture from Germanium-68 (Ge). In such a radionuclide generator, the germanium is bound to an insoluble, inert column matrix and forms a secular radioactive balance with 68Ga obtained in the hour. As a result of the limited radiochemical selectivity of the elution process, the eluate obtained is basically contaminated with the main nuclide traces, so that the eluate becomes a mixture of Ga and Ge radionuclides.

An intrathoracic schwannoma case in F-FDG PET/CT scan.

Positron emission tomography /CT images showed a moderately increased F-FDG uptake in the mass of left lung lower lobe superior segment (SUVmax: 2.71). No pathological F-FDG involvement was detected in another region of the whole body scan.

Quantitative volumetric metabolic measurement of solitary pulmonary nodules by F-18 fluorodeoxyglucose positron emission tomography-computed tomography.

Background: This study aims to evaluate the effect of quantitative volumetric metabolic measurements in F-18 fluorodeoxyglucose positron emission tomographycomputed tomography to distinguish benign and malignant solitary pulmonary nodules.

Methods: We retrospectively reviewed 78 patients (56 males; 22 females; mean age 61±11.9 years; range, 32 to 82 years) with solitary pulmonary nodules who underwent F-18 fluorodeoxyglucose positron emission tomography-computed tomography.

Hemorheology and oxidative stress in patients with differentiated thyroid cancer following I-131 ablation/metastasis treatment.

Background: Although radioiodine theraphy (RAIT) is thought to affect blood cells and oxidative stress, hemorheological alterations following dose-dependent RAIT remains unknown.

Objective: The aim of this study was to determine the effects of RAIT on hemorheological and oxidative stress parameters in patients with differentiated thyroid cancers (DTC).

Methods: Totally 31 DTC patients (mean age 46.

Intraobserver and interobserver agreement for the interpretation of 68Ga-prostate-specific membrane antigen-I&T positron emission tomography/computed tomography imaging.

Objectives: The use of Ga-prostate-specific membrane antigen positron emission tomography/computed tomography is spreading due to its clinical benefits. In this study, we aim to determine the intra- and interobserver agreement levels of Ga- prostate-specific membrane antigen-I&T positron emission tomography/computed tomography according to molecular imaging tumor-lymph node-metastases reporting system.

Materials And Methods: Eighty prostate cancer patients and underwent Ga- prostate-specific membrane antigen positron emission tomography/computed tomography were blindly evaluated twice by four nuclear medicine specialists at intervals of 4 weeks.

Incidental “Urinoma” in F-FDG PET/CT Scan.

F-FDG PET/CT scanning was performed for the primary staging of a 47-year-old man with urothelial carcinoma. The patient underwent biopsy by ureteroscopy 15 days ago and the PET images revealed F-FDG accumulation in the right retroperitenal region, compatible with an “urinoma”.

Hemorheological dysfunction in cardiac syndrome X.

Background: Cardiac syndrome X (CSX) is often described as angina or angina-like chest pain with a normal coronary arteriogram, yet the underlying pathophysiological mechanisms have not been fully elucidated. The aim of the current study was to determine alterations in blood rheology (erythrocyte aggregation and deformability, plasma viscosity - PV) in patients with CSX.

Methods: The study comprised 26 CSX patients (55.

The role of 18F-FDG PET-CT in the detection of unknown primary malignancy: a retrospective study.

Background/aim: This study aimed to retrospectively evaluate the role of 18F-FDG PET/CT imaging in the detection of unknown primary tumor sites in patients with a suspicious malignancy.

Materials And Methods: We retrospectively examined the 18F-FDG PET/CT images of 50 unknown primary malignancy patients. The malignancy of the lesions with increased 18F-FDG uptake on PET images was defined by interpreting the nondiagnostic CT images that were obtained with the PET study.

The Role of Myocardial Perfusion Gated SPECT Study in Women with Coronary Artery Disease: A Correlative Study.

Objective: We aimed to evaluate the role of gated myocardial perfusion SPECT (MPS) and to investigate whether only the invasive coronary angiography (CAG) is sufficient in the diagnosis of the coronary artery disease (CAD) in women.

Material And Methods: Sixty-four women (62±10 years) with known CAD were included in this study. They had echocardiography (ECHO), stress/rest gated MPS and invasive CAG.

Decreased plasma adiponectin concentrations in patients with syndrome X.

Objective: The levels of adiponectin, an anti-atherogenic protein, are decreased in patients with coronary artery disease. Syndrome X is associated with endothelial dysfunction, which is a key feature in the evolution of atherosclerosis. We sought to determine whether serum adiponectin levels are decreased in patients with syndrome X.

Does hypothyroidism affect gastrointestinal motility?

Background: Gastrointestinal motility and serum thyroid hormone levels are closely related. Our aim was to analyze whether there is a disorder in esophagogastric motor functions as a result of hypothyroidism.

Materials And Methods: The study group included 30 females (mean age +/- SE 45.

Scintigraphic evaluation of gallbladder motor functions in H pylori positive and negative patients in the stomach with dyspepsia.

Aim: To evaluate the relationship between gallbladder (GB) motor function and H pylori infection in the stomach.

Methods: All cases (86) underwent the 14C urea breath test (UBT). 14C-UBT was found as positive in 58 and negative in 28 dyspeptic patients.