Publications by authors named "Olga Y Alekseeva"
Article Synopsis
- Bone and muscle tissues are highly affected by various forms of low gravity, particularly simulated microgravity (sμg), leading to significant changes in bone marrow (BM) in an experimental mouse model.
- Male C57Bl/6N mice were categorized into three groups for a study that assessed how hindlimb suspension (HS) and subsequent short-term reloading (RL) affected the quantity and functionality of BM mononucleated cells (MNCs), as well as their hematopoietic and stromal progenitors.
- Results showed that HS caused a significant reduction in MNCs and disrupted their proliferation and differentiation, while RL partially restored stromal precursor activity but failed to completely recover hematopoietic cell functions.
It is well known that blood lipoproteins (LPs) are multimolecular complexes of lipids and proteins that play a crucial role in lipid transport. High-density lipoproteins (HDL) are a class of blood plasma LPs that mediate reverse cholesterol transport (RCT)-cholesterol transport from the peripheral tissues to the liver. Due to this ability to promote cholesterol uptake from cell membranes, HDL possess antiatherogenic properties.
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