Publications by authors named "Olga V Pyankova"
Article Synopsis
- Microgravity and space radiation are important factors that can cause health problems for astronauts during space flight.
- The study found that being in space affects human cells in ways like making them softer and changing cell structures, which didn't happen as much on Earth.
- Microgravity and space radiation have different effects on cells: microgravity helps cells grow and use energy better, while space radiation can cause inflammation and damage, so we need to treat them differently to keep astronauts healthy.
Article Synopsis
- - Capillary endothelial cells play a crucial role in maintaining homeostasis, and their dysfunction can lead to diseases, especially when exposed to microgravity, which negatively impacts astronauts' physiology.
- - The study examined how hypergravity affects human microvascular endothelial cells (HMEC-1) by observing changes in cell structure, gene expression, and motility at different gravity levels.
- - Results indicated that hypergravity enhances cell stiffness, motility, and functions, producing beneficial effects that counteract the negative impacts of microgravity, enhancing understanding of endothelial cell responses.
The genes ABCC8 and KCNJ11 have received intense focus in type 2 diabetes mellitus (T2DM) research over the past two decades. It has been hypothesized that the p.E23K (KCNJ11) mutation in the 11p15.
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