Publications by authors named "Olga V Mikolaichuk"

Article Synopsis
  • * The compound demonstrated good hemocompatibility and antioxidant properties, but did not show effective antiradical activity throughout its tested concentrations.
  • * In vitro tests indicated the compound has varying cytotoxic effects on different cancer cell lines, suggesting possible cancer-fighting mechanisms through inhibition of the HIF pathway.
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Unlabelled: The reaction of 5-aryl--tetrazoles with adamantan-1-ol in concentrated sulfuric acid proceeds regioselectively with the formation of the corresponding 2-adamantyl-5-aryl-2-tetrazoles. Nitration of these compounds leads to 2-(adamantan-1-yl)-5-(3-nitroaryl)-2tetrazoles. The structures and composition of the obtained novel 2-adamantyl-5-aryltetrazoles were proven by IR spectroscopy, H and C NMR spectroscopy, high-resolution mass spectrometry, and also by X-ray structural analysis.

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