Spatial and temporal uncertainty in climatic impacts on watershed systems.

Evaluating the uncertainty of climatic impacts on watershed systems is critical in planning for water supplies, water allocation, and demand at multiple scales. With the increasing frequency of water crises worldwide, understanding the nature of climatic impacts along spatial and temporal dimensions is vital to the development of timely, and spatially relevant mitigation options. This study aims to quantify the nature of hydrologic uncertainties at a spatial and temporal dimension in a regional watershed system under scenarios of varying climatic uncertainties.

Genome-Wide Approach to the CD4 T-Cell Response to Human Herpesvirus 6B.

Human herpesvirus 6 (HHV-6) and cytomegalovirus (CMV) are population-prevalent betaherpesviruses with intermittent lytic replication that can be pathogenic in immunocompromised hosts. Elucidation of the adaptive immune response is valuable for understanding pathogenesis and designing novel treatments. Knowledge of T-cell antigens has reached the genome-wide level for CMV and other human herpesviruses, but study of HHV-6 is at an earlier stage.